766556-61-0

Basic information

• Product Name: 4-(2-OXOHEXAHYDROPYRIMIDIN-1-YL)BENZOIC ACID
• Synonyms: 4-(2-OXOHEXAHYDROPYRIMIDIN-1-YL)BENZOIC ACID;4-(2-Oxotetrahydropyrimidin-1(2H)-yl)benzoic acid
• CAS NO: 766556-61-0
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.227
• Mol File: 766556-61-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-OXOHEXAHYDROPYRIMIDIN-1-YL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-OXOHEXAHYDROPYRIMIDIN-1-YL)BENZOIC ACID(766556-61-0)
• EPA Substance Registry System: 4-(2-OXOHEXAHYDROPYRIMIDIN-1-YL)BENZOIC ACID(766556-61-0)

Safety Data

• Hazardous Substances Data: 766556-61-0(Hazardous Substances Data)

Upstream product

• 619-45-4 4-methoxycarbonyl aniline 
• 766556-60-9 4-(2-oxo-tetrahydro-pyrimidin-1-yl)-benzoic acid methyl ester 

Relevant articles and documents

SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa

In the search of Factor Xa (FXa) inhibitors structurally different from the pyrazole-based series, we identified a viable series of enantiopure cis-(1R,2S)-cycloalkyldiamine derivatives as potent and selective inhibitors of FXa. Among them, cyclohexyldiam

LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS

The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trysin-like serine proteases, specifically factor Xa.