- Synthesis and evaluation of novel sulfenamides as novel anti Methicillin-resistant Staphylococcus aureus agents
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A total of 29 novel sulfenamide compounds were synthesized, spectroscopically characterized and evaluated in vitro for antimicrobial activity against various infectious pathogens. Compounds 1b and 2c exhibited potent inhibition against clinical Methicillin-resistant Staphylococcus aureus (MRSA) strains with minimum inhibitory concentration (MIC) values of 1.56 μg/mL.
- Shang, Jian-Li,Guo, Hui,Li, Zai-Shun,Ren, Biao,Li, Zheng-Ming,Dai, Huan-Qin,Zhang, Li-Xin,Wang, Jian-Guo
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p. 724 - 727
(2013/02/25)
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- Synthesis and biological evaluation of nonsymmetrical aromatic disulfides as novel inhibitors of acetohydroxyacid synthase
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46 Novel nonsymmetrical aromatic disulfides containing [1,3,4]thiadiazole or [1,3,4]oxadiazole groups were synthesized and their biological activities were evaluated as inhibitors of acetohydroxyacid synthase (AHAS, EC 2.2.1.6). Besides their strong in vitro inhibition against plant AHAS, compounds 3e and 3f also display 80-100% post-emergence herbicidal activities in greenhouse bioassay at 1500 g/ha dosage. The assay of exogenous branched-chain amino acids supplementation on rape root growth of 3e suggests that the herbicidal activity has relationship with AHAS inhibition.
- Li, Zai-Shun,Wang, Wei-Min,Lu, Wei,Niu, Cong-Wei,Li, Yong-Hong,Li, Zheng-Ming,Wang, Jian-Guo
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p. 3723 - 3727
(2013/07/25)
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- An efficient preparative route to substituted alkyl benzenesulfenates, versatile reagents for site-selective sulfenylative cyclizations
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A versatile procedure for the synthesis of alkyl benzenesulfenates possessing varied patterns of nuclear substitution is described.
- Harring, Scott R.,Livinghouse, Tom
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p. 893 - 902
(2007/10/03)
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- Synthesis of Sequential Polydepsipeptides Involving Depsipeptide Formation by the 2-Nitrophenylsulphenyl N-Carboxy α-Amino Acid Anhydride (Nps-NCA) Method
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Sequential polydepsipeptides containing a tripeptide sequence Ala-Ala-Glu(OEt) and various α-hydroxy acids have been successfully prepared by polycondensation of tetradepsipeptide pentachlorophenyl esters.The latter were synthesized by preparation of didepsipeptide free acids by the Nps-NCA method followed by active esterification and peptide chain elongation by the so-called 'back-up' procedure.
- Katakai, Ryoichi
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p. 2249 - 2252
(2007/10/02)
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- Sulphur-substituted Organotin Compounds. Part 8. Preparation and Reactions of 3-(p-Tolylthio)propyl- and 4-(p-Tolylthio)butyl-triphenyltin. Interactions with Tetracyanoethylene
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The reactions of SnPh3 (n= 3 or 4) with mercury(II) chloride, bromine and iodine lead to phenyl-tin bond cleavage.In contrast, reactions with methyl iodide provide SnPh3 and MeSC6H4Me-p.Charge-transfer adducts are formed between SnPh3 (n= 1-4) and tetracyanoethylene or p-bromoanil.The values of λmax. of the complexes indicate similar donor character for SnPh3 (n= 2,3, or 4); however, the compound SnPh3(CH2SC6H4Me-p) is a stronger donor.
- Wardell, James L.,Wigzell, John McM.
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p. 2321 - 2326
(2007/10/02)
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