There are provided a novel compound, i.e., a 2-piperazino-4-substituted-5,6-alkylenepyrimidine derivative represented by the formula: STR1 wherein Y, Z and n are defined in the specification and claims, and a pharmaceutically acceptable acid addition salt
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(2008/06/13)
Pyrimidine derivatives I. Synthesis of hypoglycemic 2-piperazino-5,6-polymethylenepyrimidines 5,6-polymethylenepyrimidines
Synthesis and hypoglycemic activity of 36 novel 2,4-diamino-5,6-polymethylenepyrimidine derivatives are described. Derivatives containing piperazino groups at position 2 showed a potent hypoglycemic activity and concomitantly inhibited platelet aggregation.
Sekiya,Hiranuma,Kanayama,Hata
p. 317 - 322
(2007/10/02)
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