769124-05-2 Usage
Uses
Used in Pharmaceutical Research:
4-Thiazolecarboxylic acid, 2-ethyl-(9CI) is employed as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block for the creation of new drugs and biologically active molecules, contributing to the advancement of medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, 4-Thiazolecarboxylic acid, 2-ethyl-(9CI) serves as a versatile reagent for the preparation of a wide range of organic compounds. Its carboxylic acid group allows for various chemical reactions, such as esterification, amidation, and condensation, enabling the synthesis of complex organic molecules with potential applications in different industries.
Used in Drug Development:
4-Thiazolecarboxylic acid, 2-ethyl-(9CI) is used as a precursor in the development of new drugs, particularly those targeting specific biological pathways or receptors. Its incorporation into drug molecules can enhance their efficacy, selectivity, and pharmacokinetic properties, leading to improved therapeutic outcomes.
Used in Chemical Research:
In the context of chemical research, 4-Thiazolecarboxylic acid, 2-ethyl-(9CI) is utilized to study the properties and reactivity of thiazole-containing compounds. This knowledge can be applied to the design of novel chemical processes and the discovery of new chemical entities with potential applications in various fields, including materials science, agrochemistry, and environmental chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 769124-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,9,1,2 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 769124-05:
(8*7)+(7*6)+(6*9)+(5*1)+(4*2)+(3*4)+(2*0)+(1*5)=182
182 % 10 = 2
So 769124-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NO2S/c1-2-5-7-4(3-10-5)6(8)9/h3H,2H2,1H3,(H,8,9)
769124-05-2Relevant articles and documents
PHENOXYPYRIDINYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PDE4 MEDIATED DISEASE STATES
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Page/Page column 133, (2009/12/27)
The present invention provides a compound of a formula (I), wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE4 mediated disease state.
A catch-and-release strategy for the combinatorial synthesis of 4-acylamino-1,3-thiazoles as potential CDK5 inhibitors
Larsen, Scott D.,Stachew, Carl F.,Clare, Paula M.,Cubbage, Jerry W.,Leach, Karen L.
, p. 3491 - 3495 (2007/10/03)
Two-dimensional libraries of 4-acylamino-1,3-thiazoles 9 were prepared via Curtius rearrangement of 1,3-thiazole-4-carbonyl azides 6, trapping of the intermediate isocyanates with oxime resin, and thermal regeneration of the isocyanates from the washed resin in the presence of nucleophiles. Several compounds proved to be selective inhibitors of CDK5/p25 versus the closely homologous CDK2/cyclin A enzyme, with the best analogue (43) possessing over 100-fold selectivity.
