- Iron-Catalyzed Primary C—H Amination of Sulfamate Esters and Its Application in Synthesis of Azetidines?
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The direct amination of unactivated primary C—H bonds is extremely challenging due to their inert nature. Herein, we report an intramolecular primary C—H amination of sulfamate esters using an iron catalyst derived from iron(II) triflate and bipyridine. An array of oxathiazinanes were synthesized in moderate to good yields, which were further converted into biologically important azetidines by a one-pot procedure. This research demonstrates the potential of applying simple nitrogen ligands in iron-catalyzed C—H functionalization and offers an accessible alternative to state-of-the-art iron-nitrene chemistry.
- Zhang, Yan,Zhong, Dayou,Usman, Muhammad,Xue, Peng,Liu, Wen-Bo
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supporting information
p. 1651 - 1655
(2020/10/19)
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- PROCESSES FOR PREPARING COMPLEXES COMPRISING RHODIUM(II) AND CARBOXYLATE LIGANDS
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There is provided herein a process for the preparation of a complex of formula (I): Rh(II)2 Xn, wherein X and n have meanings provided in the description, comprising the step of reacting: (a) a source of Rh(III); and (b) a source of
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Page/Page column 75-77
(2019/02/15)
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- PROCESSES FOR PREPARING STERICALLY CONGESTED DICARBOXYLIC ACID LIGANDS AND PRODUCTS THEREOF
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There is provided herein a process for the preparation of a compound of formula I (I) or a salt thereof, wherein X1 to X4, Y1 to Y4, Z and n each have meanings provided in the description. There is also provided
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Page/Page column 68-69
(2017/08/21)
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- Entrapment of a dirhodium tetracarboxylate unit inside the aromatic bowl of a calix[4]arene: Unique catalysts for C-H amination
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Unique calix[4]arene-derived, tetracarboxylate dirhodium(ii) inclusion complexes have been prepared and evaluated as catalysts for C-H amination. The Royal Society of Chemistry.
- Brodsky, Benjamin H.,Bois, J. Du
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p. 4715 - 4717
(2007/10/03)
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- Intramolecular asymmetric amidations of sulfonamides and sulfamates catalyzed by chiral dirhodium(II) complexes
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Enantioselective intramolecular amidation of aliphatic sulfonamides was achieved for the first time by means of chiral carboxylatodirhodium(II) catalysts in conjunction with PhI(OAc)2 and MgO in high yields and with enantioselectivities of up to 66% (Scheme 3, Table 1). The best results were obtained with [Rh2{(S)-nttI)4] and [Rh 2{(R)-ntv)4] as catalysts ((S)-nttl = (αS)-α- (tert-butyl)-1,3-dioxo-2H-benz[de]isoquinoline-2-acetato, (R)-nto = (αR)-α-isopropyl-1,3-dioxo-2H-benz[de] isoquinoline-2-acetato). In addition, these carboxylatodirhodium(II) catalysts were also efficient in intramolecular amidations of aliphatic sulfamates esters, although the enantioselectivity of these latter reactions was significantly lower (Scheme 4, Table 3).
- Fruit, Corinne,Mueller, Paul
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p. 1607 - 1615
(2007/10/03)
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- Cyclic sulfamidates as vehicles for the synthesis of substituted lactams
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(Chemical Equation Presented) A structurally diverse series of mono- and disubstituted 1,2- and 1,3-cyclic sulfamidates react with stabilized enolates, including malonate and phosphonoacetate variants, to provide, after lactamization, substituted and α-fu
- Bower, John F.,Svenda, Jakub,Williams, Andrew J.,Charmant, Jonathan P. H.,Lawrence, Ron M.,Szeto, Peter,Gallagher, Timothy
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p. 4727 - 4730
(2007/10/03)
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