- STRUCTURE OF 3-CHLORO-6-HYDRAZINOPYRIDAZINE IN SOLUTIONS
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It is shown by means of the fixed-structure method, UV spectroscopy and dipole-moment method that the product of the reaction of 3,6-dichloropyridazine with hydrazine in solution in methanol and acetonitrile has the 3-chloro-6-hydrazinopyridazine structur
- Buzykin, B. I.,Maksimova, A. A.,Stolyarov, A. P.,Flegontov, S. A.,Kitaev, Ju. P.
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- INHIBITORS OF FLAVIVIRIDAE VIRUSES
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Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
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Page/Page column 54
(2011/08/04)
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- N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES
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Novel N-phenyl-1,1,1-trifluoromethanesulfonamide compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo and ex vivo.
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Page/Page column 38
(2008/06/13)
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- Nucleophilic substitution of chlorine with hydrazine and methylhydrazine in chlorinated pyridazines and pyridazones
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The reactions of methylhydrazine and hydrazine hydrate with chlorinated pyridazines and pyridazones were studied.
- Baranov,Tsypin,Malin,Laskin
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p. 1997 - 2000
(2007/10/03)
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- Process for preparing N-pyrrolyl-pyridazineamine derivatives
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The present invention refers to a new process for preparing N-2,3,4,5-substituted-1H-pyrrol-1-yl)-6-substituted amino-3-pyridazineamine, known as antihypertensive agents. The process is characterized in that a suitable 3,6-dihalogenopyridazine is reacted with hydrazine hydrate or other hydrazine derivatives of formula NH2 NHR, the obtained compound is reacted with a suitable dicarbonyl compound yielding first an alcandione-bis-[6-halogen-3-pyridazininyl]hydrazone, and then a 6-halogen-3-pyrrolylpyridazineamine derivative which is in turn reacted with an amine to yield the desired compounds.
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