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76958-67-3

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Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin
The resorcylic acid lactones (RAL) are endowed with diverse biological activity ranging from transcription factor modulators (zearalenone and zearalenol) to HSP90 inhibitors (radicicol and pochonin D) and reversible (aigialomycin D) as well as irreversibl
Dakas, Pierre-Yves,Jogireddy, Rajamalleswaramma,Valot, Gaelle,Barluenga, Sofia,Winssinger, Nicolas
supporting information; experimental part
p. 11490 - 11497
(2010/04/28)

Convergent stereospecific synthesis of LL-Z1640-2 (or C292), hypothemycin and related macrolides. Part 2
The total synthesis of C292 (or LL-Z1640-2) and hypothemycin has been achieved. The 14-membered ring formation was achieved either via an intramolecular Suzuki coupling or much more efficiently via a Mitsunobu macrolactonisation. Reaction conditions were
Sellès, Patrice,Lett, Robert
p. 4627 - 4631
(2007/10/03)

More Articles about upstream products of 76958-67-3

Chemical Properties

Melting Point: 170-172℃
Boiling Point: 673.1°C at 760 mmHg
Flash Point:242.7°C
Density: 1.343g/cm³
Solubility:DMSO: soluble
Storage Temp.:?20°C
Vapor Pressure: 4.92E-19mmHg at 25°C
PSA: 125.82000
LogP: 1.02690

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