Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: Thiol- mediated nitric oxide release and biological evaluation
4-Phenyl-3-furoxancarbonitrile (2) affords nitric oxide under the action of thiol cofactors. Two principal products were isolated in the reaction with thiophenol: the phenylcyanoglyoxime (6) and 5-amino-3-phenyl-4- (phenylthio)isoxazole (7). Mechanisms wh
Medana,Ermondi,Fruttero,Di Stilo,Ferretti,Gasco
p. 4412 - 4416
(2007/10/02)
Voie d'acces aux amino-5 isoxazoles substitues en 4 par un groupement SR
The reaction with hydroxylamine of bromoderivatives 2, obtained from aldehydes, provides, in most cases with good yields, 5-isoxazolamines 3. (13)C NMR data are given.
Pochat, Francis
p. 3755 - 3758
(2007/10/02)
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