77239-98-6 Usage
Uses
Bromadol is an analytical reference material categorized as an opioid. This product is intended for research and forensic applications.
Clinical claims and research
Bromadol, also referred to as BDPC (trans-4-(p-bromophenyl)-4-(dimethylamino)-1- phenethylcyclohexanol), was amongst the most potent and efficacious compounds studied here. Using a standard mouse hot plate assay, Liu et al. (2003) previously suggested that the analgesic potency of bromadol may be around 2.9 times that of fentanyl (Sharma et al. 2019). The herein reported in vitro potencies for βarr2 and mini-Gi recruitment echo this, as the EC50 values for bromadol were 7.6- and 10.8-fold lower than those obtained for fentanyl using the same respective assays. However, as discussed further, it remains difficult to directly compare in vivo analgesic potency to in vitro potency values. Interestingly, the in vivo antinociceptive potency reported by Liu et al. (2003) was greater than what may be expected based on opioid receptor binding affinity data (Sharma et al. 2019). Although determination of binding affinity was outside the scope of the current study, the high in vitro efficacy and potency at MOR reported here, may provide an explanation for this.
Check Digit Verification of cas no
The CAS Registry Mumber 77239-98-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,3 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77239-98:
(7*7)+(6*7)+(5*2)+(4*3)+(3*9)+(2*9)+(1*8)=166
166 % 10 = 6
So 77239-98-6 is a valid CAS Registry Number.
