773134-56-8

Basic information

• Product Name: ethyl 2-chloro-6-fluoro-benzoat
• Synonyms: ethyl 2-chloro-6-fluoro-benzoat;Ethyl 2-chloro-6-fluorobenzoate
• CAS NO: 773134-56-8
• Molecular Formula: C₉H₈ClFO₂
• Molecular Weight: 202.6100232
• Mol File: 773134-56-8.mol

Chemical Properties

• Boiling Point: 252.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.266±0.06 g/cm3(Predicted)
• CAS DataBase Reference: ethyl 2-chloro-6-fluoro-benzoat(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-chloro-6-fluoro-benzoat(773134-56-8)
• EPA Substance Registry System: ethyl 2-chloro-6-fluoro-benzoat(773134-56-8)

Safety Data

• Hazardous Substances Data: 773134-56-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-chloro-6-fluoro-benzoat is used as an intermediate in the production of various pharmaceuticals. It plays a crucial role in the synthesis of drugs, contributing to the development of new medications and improving the efficacy of existing ones.
Used in Agrochemical Industry:
In the agrochemical industry, ethyl 2-chloro-6-fluoro-benzoat is utilized as an intermediate for the synthesis of various agrochemicals. It helps in the development of pesticides, herbicides, and other agricultural chemicals, enhancing crop protection and yield.
Safety Precautions:
It is essential to handle ethyl 2-chloro-6-fluoro-benzoat with care and use appropriate safety measures when working with it. This chemical can be harmful if inhaled, ingested, or comes in contact with skin or eyes. Proper handling and storage are necessary to ensure the safety of individuals and the environment.

InChI:InChI=1/C9H8ClFO2/c1-2-13-9(12)8-6(10)4-3-5-7(8)11/h3-5H,2H2,1H3

Upstream product

• 443-26-5 2-fluoro-benzoic acid ethyl ester 

Downstream Products

• 1436501-85-7 6-chloro-N-(3-(4,4-dimethylcyclohexyl)-4-oxo-3,4-dihydrophthalazin-6-yl)-2-fluoro-3-(pivalamidomethyl)benzamide 
• 1449737-61-4 ethyl 6-chloro-2-fluoro-3-((3-hydroxy-2,2-dimethylpropanamido)methyl)benzoate 
• 1449737-77-2 ethyl 6-chloro-2-fluoro-3-((3-fluoro-2,2-dimethylpropanamido)methyl)benzoate 
• 1449735-79-8 6-chloro-2-fluoro-3-(pivalamidomethyl)-N-(1-((3-(trifluoromethyl)phenyl)amino)isoquinolin-5-yl)benzamide 
• 1360624-19-6 N-(3-amino-4-chloro-2-fluorobenzyl)pivalamide 
• 1449737-60-3 6-chloro-2-fluoro-3-((3-hydroxy-2,2-dimethylpropanamido)methyl)benzoic acid 
• 1294496-84-6 ethyl 6-chloro-2-fluoro-3-formylbenzoate 
• 1427158-87-9 6-chloro-2-fluoro-N-(3-((3-fluorophenyl)amino)isothiazolo[4,5-b]pyridin-7-yl)-3-(pivalamidomethyl)benzamide 
• 1427158-88-0 4-nitrophenyl 6-chloro-2-fluoro-3-(pivalamidomethyl)benzoate 
• 1427158-55-1 6-chloro-2-methoxy-3-(pivalamidomethyl)benzoic acid 
• 1294496-88-0 6-chloro-2-fluoro-3-((pivalamido)methyl)benzoic acid 
• 1294496-87-9 ethyl 6-chloro-2-fluoro-3-((pivalamido)methyl)benzoate 
• 1294496-86-8 ethyl 3-(aminomethyl)-6-chloro-2-fluorobenzoate 
• 1294496-85-7 ethyl 6-chloro-2-fluoro-3-((hydroxyimino)methyl)benzoate 

Relevant articles and documents

Regio- and chemoselective C-H chlorination/bromination of electron-deficient arenes by weak coordination and study of relative directing-group abilities

It's all relative: A practical and efficient PdII-catalyzed regio- and chemoselective chlorination/bromination has been developed for the facile synthesis of a broad range of aromatic chlorides. The reaction demonstrates excellent reactivity, good functional-group tolerance, and high yields. A preliminary study was conducted to evaluate relative directing-group abilities of various functionalities. Copyright