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2-(1,3-Oxazol-5-yl)aniline, with the molecular formula C9H8N2O, is an aromatic amine characterized by the presence of an oxazole ring. This unique structure endows it with potential applications in various fields, including pharmaceuticals, dyes, and organic synthesis. Its aromatic nature also suggests possible biological activity, making it a candidate for drug discovery and development.

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  • 774238-36-7 Structure
  • Basic information

    1. Product Name: 2-(1,3-OXAZOL-5-YL)ANILINE
    2. Synonyms: 2-(1,3-OXAZOL-5-YL)ANILINE;BUTTPARK 154\16-25;5-(2-Aminophenyl)-1,3-oxazole;2-(5-Oxazolyl)aniline;2-(1,3-Oxazol-5-yl)aniline97%
    3. CAS NO:774238-36-7
    4. Molecular Formula: C9H8N2O
    5. Molecular Weight: 160.17
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 774238-36-7.mol
  • Chemical Properties

    1. Melting Point: 54 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(1,3-OXAZOL-5-YL)ANILINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(1,3-OXAZOL-5-YL)ANILINE(774238-36-7)
    11. EPA Substance Registry System: 2-(1,3-OXAZOL-5-YL)ANILINE(774238-36-7)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 774238-36-7(Hazardous Substances Data)

774238-36-7 Usage

Uses

Used in Pharmaceutical Industry:
2-(1,3-OXAZOL-5-YL)ANILINE is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure may offer novel properties and activities that can be harnessed in medicinal chemistry.
Used in Dye Industry:
In the dye industry, 2-(1,3-OXAZOL-5-YL)ANILINE is used as a building block for the creation of new dyes. Its aromatic and oxazole-containing structure can influence the color and properties of the resulting dyes, offering a wide range of applications in various industries that require colorants.
Used in Organic Synthesis:
2-(1,3-OXAZOL-5-YL)ANILINE is utilized as a key intermediate in organic synthesis, where it can be incorporated into more complex molecules. Its reactivity and structural features make it a valuable component in the preparation of a variety of organic compounds.
Used in Research and Development:
In the realm of research, 2-(1,3-OXAZOL-5-YL)ANILINE is used as a building block for the development of new materials and chemical reactions. Its unique structure and potential biological activity make it an interesting subject for scientific exploration and innovation.
Due to its aromatic nature, 2-(1,3-OXAZOL-5-YL)ANILINE has the potential to exhibit biological activity, which could be of interest in drug discovery and development. However, its specific uses and properties may vary depending on the exact application and formulation.

Check Digit Verification of cas no

The CAS Registry Mumber 774238-36-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,4,2,3 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 774238-36:
(8*7)+(7*7)+(6*4)+(5*2)+(4*3)+(3*8)+(2*3)+(1*6)=187
187 % 10 = 7
So 774238-36-7 is a valid CAS Registry Number.

774238-36-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(5-Oxazolyl)aniline

1.2 Other means of identification

Product number -
Other names 2-(1,3-OXAZOL-5-YL)ANILINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:774238-36-7 SDS

774238-36-7Relevant articles and documents

Synthesis of 4-substituted oxazolo[4,5-c]quinolines by direct reaction at the C-4 position of oxazoles

Akula, Mahesh,Thigulla, Yadagiri,Davis, Connor,Jha, Mukund,Bhattacharya, Anupam

, p. 2600 - 2605 (2015)

A facile synthesis of 4-aryl substituted oxazolo[4,5-c]quinolines has been described via a modified Pictet-Spengler method and using Cu(TFA)2 as a catalyst. The developed methodology directly functionalizes the C-4 position of oxazoles without

COMPOUNDS USEFUL FOR INHIBITING CHK1

-

Page/Page column 45, (2008/06/13)

Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as ther-apeutic agents, for example, in treating cancer and oth

HYDRAZONE DERIVATIVE

-

Page/Page column 22, (2010/11/08)

A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc., a salt thereof or a solvate thereof; and an agent for inhibiting aggregation and/or deposition of an amyloid protein or an amyloid-like protein, which comprises the compound, a salt thereof or a solvate thereof

Imidazoline derivatives as alpha-1A adrenoceptor ligands

-

Page/Page column 40, (2010/02/11)

Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.

2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.

Navas 3rd., Frank,Bishop, Michael J,Garrison, Deanna T,Hodson, Stephen J,Speake, Jason D,Bigham, Eric C,Drewry, David H,Saussy, David L,Liacos, James H,Irving, Paul E,Gobel, M Jeffrey

, p. 575 - 579 (2007/10/03)

A series of 2'-heteroaryl and 2'-oxime anilinomethylimidazolines was prepared and evaluated in in vitro functional assays for cloned human alpha1A, alpha1B, and alpha1D receptor subtypes. Potent and selective alpha1A agonists have been identified in these series.

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