775293-15-7Relevant articles and documents
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization
Kattar, Solomon D.,Surdi, Laura M.,Zabierek, Anna,Methot, Joey L.,Middleton, Richard E.,Hughes, Bethany,Szewczak, Alexander A.,Dahlberg, William K.,Kral, Astrid M.,Ozerova, Nicole,Fleming, Judith C.,Wang, Hongmei,Secrist, Paul,Harsch, Andreas,Hamill, Julie E.,Cruz, Jonathan C.,Kenific, Candia M.,Chenard, Melissa,Miller, Thomas A.,Berk, Scott C.,Tempest, Paul
scheme or table, p. 1168 - 1172 (2009/08/07)
The successful application of both solid and solution phase library synthesis, combined with tight integration into the medicinal chemistry effort, resulted in the efficient optimization of a novel structural series of selective HDAC1/HDAC2 inhibitors by