77532-90-2

Basic information

• Product Name: 2-CYANO-4-FLUOROBENZALDEHYDE
• Synonyms: 2-CYANO-4-FLUOROBENZALDEHYDE;Benzonitrile, 5-fluoro-2-formyl- (9CI);5-Fluoro-2-formylbenzonitrile;C90154
• CAS NO: 77532-90-2
• Molecular Formula: C₈H₄FNO
• Molecular Weight: 149.12
• Product Categories: HALIDE;ALDEHYDE
• Mol File: 77532-90-2.mol

Chemical Properties

• Melting Point: 120-122 °C
• Boiling Point: 286.3 °C at 760 mmHg
• Flash Point: 126.9 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 0.00266mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CYANO-4-FLUOROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-4-FLUOROBENZALDEHYDE(77532-90-2)
• EPA Substance Registry System: 2-CYANO-4-FLUOROBENZALDEHYDE(77532-90-2)

Safety Data

• Hazardous Substances Data: 77532-90-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-CYANO-4-FLUOROBENZALDEHYDE serves as a crucial intermediate in the synthesis of pharmaceuticals. It is utilized for its ability to contribute to the development of new drugs, enhancing the range of therapeutic options available.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CYANO-4-FLUOROBENZALDEHYDE is employed as an intermediate in the production of various agrochemicals, which are essential for crop protection and enhancement of agricultural yields.
Used in Dye and Pigment Production:
2-CYANO-4-FLUOROBENZALDEHYDE is also used in the manufacturing process of dyes and pigments, where its chemical properties contribute to the creation of a diverse array of colorants for different applications.
Safety Precautions:
It is important to handle 2-CYANO-4-FLUOROBENZALDEHYDE with care due to its potential hazards. It may be harmful if ingested, inhaled, or if it comes into contact with the skin, and it can cause skin and eye irritation. Adequate safety measures should be taken to mitigate these risks during its use and production.

InChI:InChI=1/C8H4FNO/c9-8-2-1-6(5-11)7(3-8)4-10/h1-3,5H

Upstream product

• 77532-85-5 2-(dibromomethyl)-5-fluorobenzonitrile 

Downstream Products

• 1049693-80-2 2-(2,2-dibromovinyl)-5-fluorobenzonitrile 
• 1233881-24-7 (Z)-6-fluoro-3-(3-phenylprop-2-ynylidene)isoindolin-1-one 

Relevant articles and documents

Tetrazole derivative and preparation thereof, pharmaceutical composition containing tetrazole derivative and application of tetrazole derivative

The invention discloses a tetrazole derivative having a structure represented by a general formula I, wherein R1 is H, a C1-C3 alkyl chain or a halogenated alkyl chain. The invention also discloses acomposition containing the tetrazole derivative and an application of the tetrazole derivative in preparation of medicines for preventing and resisting cerebral apoplexy. Repeated experiments prove that the compound has an obvious inhibition effect on ADP-induced platelet aggregation activity, and has a good protection effect on OGD/R-damaged primary mouse nerve cell models and good rat oral medicine pharmacokinetic properties. Therefore, the compound disclosed by the invention can be used as a neuroprotective agent to be applied to medicines for treating and preventing cerebral apoplexy.

Benzotetrazole derivatives and preparation thereof, pharmaceutical compositions containing benzotetrazole derivatives and application of benzotetrazole derivatives

The invention discloses benzotetrazole derivatives. The benzotetrazole derivatives have a structure represented by a general formula I or a general formula I'. In the general formula I or the generalformula I', R1 is a C3-C5 alkyl chain or a halogenated a

A tandem elimination-cyclization-suzuki approach: Efficient one-pot synthesis of functionalized (Z)-3-(arylmethylene)isoindolin-1-ones

(Chemical Equation Presented) A novel and efficient one-pot regioselective elimination-cyclization-Suzuki approach was developed to afford (Z)-3-arylmethyleneisoindolin-1-ones in good to excellent yields from easily accessible o-gem-dihalovinylbenzamides and organoboron reagents.