ACYLATION OF ACYCLIC ENAMINES WITH AN EXCESSIVE AMOUNT OF PYRIDINECARBONYL CHLORIDES
Acylation of the acyclic enamines (1a and d) and (6a) with an excessive amount of isonicotinoyl or nicotinoyl chloride provided a simple preparation of the spiranes (2, 3, and 7) or the 1,6-naphtyridines (4 and 5) respectively, of which the latter has an analogous structure of nalidixic acid, a powerful antibacterial agent.
Naito, Takeaki,Ninomiya, Ichiya
p. 735 - 738
(2007/10/02)
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