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Heroin-7,8-oxide, also known as 6-MAM-7,8-oxide, is a derivative and potentially active metabolite of heroin. It is an opiate substance that is believed to contribute to the analgesic (pain-relieving) effects of heroin. Although its full pharmacology is not completely understood due to limited research, it is a significant compound that could help in understanding the biology of heroin use and addiction.

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  • 77632-95-2 Structure
  • Basic information

    1. Product Name: heroin-7,8-oxide
    2. Synonyms: heroin-7,8-oxide
    3. CAS NO:77632-95-2
    4. Molecular Formula: C21H23NO6
    5. Molecular Weight: 385.41042
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 77632-95-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 524.1°C at 760 mmHg
    3. Flash Point: 270.8°C
    4. Appearance: /
    5. Density: 1.43g/cm3
    6. Vapor Pressure: 4.45E-11mmHg at 25°C
    7. Refractive Index: 1.64
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: heroin-7,8-oxide(CAS DataBase Reference)
    11. NIST Chemistry Reference: heroin-7,8-oxide(77632-95-2)
    12. EPA Substance Registry System: heroin-7,8-oxide(77632-95-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 77632-95-2(Hazardous Substances Data)

77632-95-2 Usage

Uses

Used in Pharmaceutical Research:
Heroin-7,8-oxide is used as a research compound for studying the pharmacological effects of heroin. Its role in the analgesic effects, toxicity, and long-term health effects of heroin use is not well-defined, making it a valuable subject for further investigation.
Used in Addiction Studies:
Heroin-7,8-oxide is used as a key compound in addiction research, particularly in understanding the mechanisms behind heroin use and addiction. Its potential contribution to the development of addiction and the associated health risks is an area of interest for scientists and researchers.
Used in Toxicology:
Heroin-7,8-oxide is used as a toxicological agent to explore the potential toxicity of heroin and its long-term health effects. Understanding the role of this compound in the toxicity of heroin could help in the development of safer and more effective pain management strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 77632-95-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,6,3 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 77632-95:
(7*7)+(6*7)+(5*6)+(4*3)+(3*2)+(2*9)+(1*5)=162
162 % 10 = 2
So 77632-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H23NO6/c1-9(23)25-13-5-4-11-8-12-15-17-18(27-17)19(26-10(2)24)20-21(15,6-7-22(12)3)14(11)16(13)28-20/h4-5,12,15,17-20H,6-8H2,1-3H3/t12-,15-,17+,18+,19+,20-,21-/m1/s1

77632-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Diacetylmorphine 7,8-oxide

1.2 Other means of identification

Product number -
Other names Heroin 7,8-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77632-95-2 SDS

77632-95-2Synthetic route

acetic anhydride
108-24-7

acetic anhydride

morphine-7,8-oxide
77632-94-1

morphine-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
In pyridine62.9%
3-methoxymethylmorphinone
77632-93-0

3-methoxymethylmorphinone

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 81 percent / H2O2, NaOH / methanol; H2O
2: 66 percent / NaBH4 / methanol
3: 73.1 percent / 1N HCl / 20 °C
4: 62.9 percent / pyridine
View Scheme
3-methoxymethylmorphinone-7,8-oxide
77648-71-6

3-methoxymethylmorphinone-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 66 percent / NaBH4 / methanol
2: 73.1 percent / 1N HCl / 20 °C
3: 62.9 percent / pyridine
View Scheme
3-methoxymethylmorphine-7,8-oxide
77632-96-3

3-methoxymethylmorphine-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 73.1 percent / 1N HCl / 20 °C
2: 62.9 percent / pyridine
View Scheme

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