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(5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is a methyl ester derivative of cholic acid, a primary bile acid naturally occurring in the human body. This steroid compound features a unique arrangement of hydroxyl groups and a double bond at the 5th and 2nd carbon positions, which contribute to its potential therapeutic properties.

77731-10-3

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    Cas No: 77731-10-3

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    Cas No: 77731-10-3

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77731-10-3 Usage

Uses

Used in Cholesterol Metabolism Regulation:
(5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is utilized as a cholesterol metabolism regulator due to its inherent properties as a bile acid derivative. It plays a crucial role in the digestion and absorption of dietary fats, as well as the solubilization and transport of cholesterol in the body.
Used in Drug Delivery Systems:
In the pharmaceutical industry, (5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is employed as a drug carrier for targeted delivery. Its ability to interact with biological systems and transport molecules to specific sites within the body makes it a promising candidate for the development of targeted drug delivery systems, potentially improving the efficacy and reducing the side effects of various medications.
Used in Anti-Inflammatory and Immunomodulatory Applications:
(5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is used as an anti-inflammatory and immunomodulatory agent. Research has indicated that cholic acid and its derivatives, including (5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester, may possess anti-inflammatory properties and modulate immune responses, making them potential candidates for the development of novel pharmaceuticals targeting inflammatory and immune-related disorders.
Used in Pharmaceutical Development:
In the field of pharmaceutical development, (5beta,7alpha,12alpha)-7,12-Dihydroxychol-2-en-24-oic acid methyl ester is used as a starting material or intermediate in the synthesis of various drugs. Its unique structure and functional groups make it a valuable component in the creation of new therapeutic agents with diverse applications in medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 77731-10-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,7,3 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77731-10:
(7*7)+(6*7)+(5*7)+(4*3)+(3*1)+(2*1)+(1*0)=143
143 % 10 = 3
So 77731-10-3 is a valid CAS Registry Number.

77731-10-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 7a,12a-dihydroxy-5b-chol-2-enoate

1.2 Other means of identification

Product number -
Other names methyl (4R)-4-[(5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77731-10-3 SDS

77731-10-3Downstream Products

77731-10-3Relevant articles and documents

A mild one-pot method for conversion of various steroidal secondary alcohols into the corresponding olefins

Kumar, Raju Ranjith,Haveli, Shrutisagar Dattatraya,Kagan, Henri B.

experimental part, p. 1709 - 1712 (2011/09/14)

The addition of Tf2O to some hydroxy steroids in the presence of excess base directly leads to steroidal olefins. This methodology is useful for the one-pot synthesis of Δ2- or Δ3-steroids under mild conditions from the corresponding alcohols. Georg Thieme Verlag Stuttgart · New York.

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