cas 78095-19-9, (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
78095-19-9

Articles about 78095-19-9Total 2 be found

Article title
Article abstract
Author
Journal number and time
Download

8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists
A series of 2-(alkylamino)tetralins related to 8-hydroxy-2-(di-n-propylamino)tetralin (21) were prepared and tested as dopamine (DA) and 5-hydroxytryptamine (5-HT) receptor agonists. Several of the compounds were potent 5-HT agonists devoid of DA-mimetic effects. N-Ethyl or N-propyl substitution of 8-hydroxy-2-aminotetralin gave the most potent agonists. It was shown that the most potent compound, (+)-21, has the 2R configuration. 5,8-Dimethoxy-2-(di-n-propylamino)tetralin (31) was found to be a weak DA agonist devoid of 5-HT activity. The corresponding indan derivative, 4,7-dimethoxy-2-(di-n-propylamino)indan (39), has been reported to be active on both DA and 5-HT receptors. The 5-HT-stimulating properties of compounds 21 and 39 as compared to the incapability of compound 31 to activate the 5-HT receptor is tentatively explained by the assumed mode of binding of the compounds to the 5-HT receptor.
Arvidsson,Hacksell,Johansson,Nilsson,Lindberg,Sanchez,Wikstroem,Svensson,Hjorth,Carlsson
p. 45 - 51
(2007/10/02)

8-Hydroxy-2-(di-n-propylamino)tetralin, a New Centrally Acting 5-Hydroxytryptamine Receptor Agonist
-
Arvidsson, Lars-Erik,Hacksell, Uli,Nilsson, J. Lars G.,Hjorth, Stephan,Carlsson, Arvid,et al.
p. 921 - 923
(2007/10/02)

More Articles about upstream products of 78095-19-9

More Articles about downstream products of 78095-19-9

87395-03-7
(R)-8-hydroxy-2-(dipropylamino)tetralin 1-phenyltetrazoyl ather

Chemical Properties

Solubility:H2O: >10mg/mL at ±60°C (with sonication)
Storage Temp.:protect from light
PSA: 23.47000
LogP: 4.32960

Show more

Global suppliers and manufacturers of 78095-19-9total 5 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Zhuozhou Wenxi import and Export Co., Ltd
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 139.0-210.0 / Kilogram
Main Products:1
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

BOC Sciences
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:41
Country:

ZHEJIANG JIUZHOU CHEM CO.,LTD
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:26
Country:

Abcam Biochemicals
Business Type:Manufacturers
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 78095-19-9

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer