78215-54-0

Basic information

• Product Name: (+/-)-Hypophyllanthin
• Synonyms: (+/-)-Hypophyllanthin
• CAS NO: 78215-54-0
• Molecular Formula: C24H30O7
• Molecular Weight: 430.4908
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 78215-54-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+/-)-Hypophyllanthin(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-Hypophyllanthin(78215-54-0)
• EPA Substance Registry System: (+/-)-Hypophyllanthin(78215-54-0)

Safety Data

• Hazardous Substances Data: 78215-54-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(+/-)-Hypophyllanthin is used as a pharmaceutical compound for its potential therapeutic effects. It has been investigated for its anti-cancer properties, as well as other possible health benefits. (+/-)-Hypophyllanthin's unique structure and biological activities make it a promising candidate for the development of new drugs and treatments.
Used in Cancer Research:
In cancer research, (+/-)-Hypophyllanthin is used as a test compound to study its effects on various types of cancer cells. Its potential to inhibit cancer cell growth and proliferation makes it a valuable tool in understanding the mechanisms of cancer development and identifying new targets for treatment.
Used in Drug Delivery Systems:
Similar to gallotannin, (+/-)-Hypophyllanthin can also be incorporated into drug delivery systems to improve its bioavailability and therapeutic outcomes. Researchers are exploring the use of nanoparticles and other carriers to enhance the delivery of (+/-)-Hypophyllanthin to target cancer cells, potentially increasing its efficacy and reducing side effects.
Used in Natural Product Chemistry:
(+/-)-Hypophyllanthin serves as a subject of study in natural product chemistry, where researchers investigate the structure, properties, and potential applications of naturally occurring compounds. Understanding the characteristics of (+/-)-Hypophyllanthin and other lignans can lead to the discovery of new bioactive molecules and the development of novel pharmaceuticals.

Upstream product

• 82423-78-7 r-1-(3,4-dimethoxyphenyl)-t-2,c-3-bishydroxymethyl-6-methoxy-7,8-methylenedioxy-1,2,3,4-tetrahydronaphthalene 
• 74-88-4 methyl iodide 
• 78246-77-2 (6aR,9aR,10S)-5-Bromo-10-(3,4-dimethoxy-phenyl)-4-methoxy-6a,7,9a,10-tetrahydro-6H-furo[3',4':6,7]naphtho[1,2-d][1,3]dioxol-9-one 

Downstream Products

• 79606-77-2 9-(3,4-Dimethoxy-phenyl)-4-methoxy-8-methoxymethyl-naphtho[1,2-d][1,3]dioxole-7-carbaldehyde 
• 79606-76-1 (8R,9S)-9-(3,4-Dimethoxy-phenyl)-4-methoxy-8-methoxymethyl-8,9-dihydro-naphtho[1,2-d][1,3]dioxole-7-carbaldehyde 

Relevant articles and documents

Structure and Synthesis of the Aryltetralin Lignans Hypophyllanthin and Nirtetralin

Structures previously suggested for hypophyllanthin, the major aryltetralin lignan constituent of Phyllanthus niruri are shown to be incorrect.The structure r-1-(3,4-dimethoxyphenyl)-6-methoxy-t-2,c-3-bismethoxymethyl-7,8-methylenedioxy-1,2,3,4-tetrahydronaphthalene (5) now proposed is confirmed by an unambiguous synthesis.Synthesis of the congener, nirtetralin, is also described.

STRUCTURE AND SYNTHESYS OF HYPOPHYLLANTHIN, NIRTETRALIN, PHYLTETRALIN AND LINTETRALIN

Structures propounded for the four aryltetralin lignan constituents isolated from Phyllanthus niruri Linn. are confirmed by syntheses of their (+/-)-forms.