783349-78-0

Basic information

• Product Name: (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID
• Synonyms: (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID;(S)-6,6-Dimethyl-morpholine-3,4-dicarboxylic acid 4-tert-butyl ester;(S)-4-(tert-Butoxycarbonyl)-6,6-diMethylMorpholine-3-carboxylic acid;(3S)-6,6-Dimethyl-morpholine-3,4-dicarboxylic acid 4-tert-butyl ester;(S)-4-Boc-6,6-Dimethyl-morpholine-3-carboxylic acid, >=98%
• CAS NO: 783349-78-0
• Molecular Formula: C12H21 N O5
• Molecular Weight: 259.30
• Mol File: 783349-78-0.mol

Chemical Properties

• Boiling Point: 373.973°C at 760 mmHg
• Flash Point: 179.973°C
• Appearance: white crystalline powder
• Density: 1.145g/cm3
• Storage Temp.: 2-8°C
• PKA: 3.55±0.40(Predicted)
• CAS DataBase Reference: (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID(783349-78-0)
• EPA Substance Registry System: (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID(783349-78-0)

Safety Data

• Hazardous Substances Data: 783349-78-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID is used as a key intermediate for the synthesis of various pharmaceuticals, facilitating the creation of new drugs and therapeutic compounds. Its presence in the synthesis process ensures the protection of amine groups, allowing for cleaner reactions and the production of more specific and effective medications.
Used in Biotechnology Industry:
In the biotechnology sector, (S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID is utilized as a component in the synthesis of biologically active compounds. Its protective role in peptide synthesis is essential for the development of bioactive molecules with potential applications in research, diagnostics, and therapeutics.
Used in Peptide Synthesis:
(S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID is used as a protecting agent in peptide synthesis, ensuring that the amine functional groups remain intact and unreacted during the synthesis process. This protection allows for the controlled formation of peptide bonds and the production of peptides with specific sequences and functions.
Used in Small Organic Molecule Production:
(S)-4-BOC-6,6-DIMETHYL-MORPHOLINE-3-CARBOXYLIC ACID is also used as a building block in the production of small organic molecules, which are essential in various chemical and pharmaceutical applications. The BOC-protected (S)-6,6-dimethylmorpholine-3-carboxylic acid contributes to the synthesis of these molecules, enhancing their stability and reactivity in targeted reactions.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.

BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE

This invention provides beta-carboline compounds of formula (I) wherein Ring A is a substituted pyridinyl, pyrimidinyl, morpholinyl, piperidinyl, piperazinyl, pyrrolidinyl, pyranyl, tetrahydrofuranyl, cyclohexyl, cyclopentyl or thiomorpholinyl ring and R1, R2 and R3 are as described in the specification. The compounds are IKK-2 inhibitors that are useful for treating IKK-2 mediated diseases such as inflammatory diseases and cancer.