- Substituted pyrazolo-piperazines as casein kinase 1 δ/ε inhibitors
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The invention provides compounds of Formula (I): and pharmaceutically acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.
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- Synthesis of 4-Substituted Bicyclooct-1-yl Fluorides
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The main details of the synthesis of a series of 4-substituted (X) bicyclooct-1-yl fluorides (1), which were required for substituent effect studies, are presented.The synthesis of most of these compounds 1, X = NO2, CN, CONH2, COCH3, CHO, OCH3, O
- Adcock, William,Abeywickrema, Anil N.
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p. 2951 - 2957
(2007/10/02)
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