792950-21-1

Basic information

• Product Name: 1H-Tetrazole,1-(4-methylphenyl)-5-(methylsulfinyl)-(9CI)
• Synonyms: 1H-Tetrazole,1-(4-methylphenyl)-5-(methylsulfinyl)-(9CI)
• CAS NO: 792950-21-1
• Molecular Formula: C9H10N4OS
• Molecular Weight: 222.2669
• Product Categories: METHYL
• Mol File: 792950-21-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Tetrazole,1-(4-methylphenyl)-5-(methylsulfinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole,1-(4-methylphenyl)-5-(methylsulfinyl)-(9CI)(792950-21-1)
• EPA Substance Registry System: 1H-Tetrazole,1-(4-methylphenyl)-5-(methylsulfinyl)-(9CI)(792950-21-1)

Safety Data

• Hazardous Substances Data: 792950-21-1(Hazardous Substances Data)

Usage

Structure

Tetrazole derivative with a methylsulfinyl and 4-methylphenyl group attached to the tetrazole ring

Usage

Potential building block for the synthesis of bioactive compounds in pharmaceutical and chemical research, with possible applications in medicinal chemistry and drug discovery

Potential

May have potential biological activities for therapeutic purposes

Safety

Handle with caution and follow proper safety protocols for handling and storage due to potential hazards.

Upstream product

• 792950-12-0 5-methylsulfanyl-1-p-tolyl-1H-tetrazole 
• 39889-77-5 1-p-tolyl-1H-tetrazol-5-ylamine 
• 67-68-5 dimethyl sulfoxide 

Relevant articles and documents

A simple method for the preparation of 5-alkylsulfinyl-1-aryltetrazoles

A simple method is suggested for the preparation of 5-alkylsulfinyl-1- aryltetrazoles via oxidation of 5-alkylsulfanyltetrazoles with 34% peracetic acid in high yields under mild conditions. A simple method is suggested for the preparation of 5-alkylsulfinyl-1-aryltetrazoles via oxidation of 5-alkylsulfanyltetrazoles with 34% peracetic acid in high yields under mild conditions.

Tert-Butyl Nitrite Mediated Expeditious Methylsulfoxidation of Tetrazole-amines with DMSO: Metal-free Synthesis of Antifungal Active Methylsulfinyl-1H-tetrazole Derivatives

A tert-butyl nitrite mediated methyl-sulfoxidation of tetrazole-amines in neat DMSO or methyl-sulfinyl derivatives is revealed for the first time. The reaction exhibits good group tolerance, as well as highly selectivity to sulfinyl substitutions. This new protocol provides an expeditious and operationally simple procedure for C?S(O) bond construction. Preliminary bioactivity evaluation on selected products shows promising antifungal activities. (Figure presented.).