A simple and efficient one-pot synthesis of multifunctional 5-aryl-5H-thiazolo[3,2-a]pyrimidines
One-pot economical and efficient synthesis of multifunctional 5H-thiazolo[3,2-a]pyrimidines by the reaction of 4-aryl dihydrothiopyrimidines with propargyl bromide in the presence of inorganic base has been reported in very short time.
Fatima, Seerat,Sharma, Anindra,Sharma, Rahul,Tripathi, Rama P.
experimental part
p. 600 - 606
(2012/09/07)
Convenient method for synthesis of thiazolo[3,2-a]pyrimidine derivatives in a one-pot procedure
An efficient one-pot method to synthesize thiazolo[3,2-a]pyrimidine derivatives has been developed. The method involves the temperature controlled functionalization-annulation of 5-ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydro- 2(1H)-pyrimidin-2-thione (DHPM
Efficient synthesis of 5H-thiazolo[3,2-a]pyrimidines from reactions of 3,4-dihydropyrimidine-thiones with α-bromoacetone in aqueous media
An efficient and convenient method for thiazolo[3,2-a]pyrimidines from cyclization reaction of dihydropyrimidine-thiones with α-bromoacetone in aqueous media is described.