80234-65-7 Usage
Uses
Used in Pharmaceutical Industry:
(8S,15S)-DIHETE is used as a potential therapeutic agent for modulating inflammatory responses and pain perception. Its ability to cause eosinophil chemotaxis with an ED50 value of 1.5 μM makes it a candidate for treating conditions involving eosinophil migration, such as asthma and allergic reactions.
Additionally, (8S,15S)-DIHETE is used as an antagonist to counteract the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model. This application suggests its potential use in managing pain and inflammation associated with various conditions, including neuropathic and inflammatory pain disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 80234-65-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,2,3 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 80234-65:
(7*8)+(6*0)+(5*2)+(4*3)+(3*4)+(2*6)+(1*5)=107
107 % 10 = 7
So 80234-65-7 is a valid CAS Registry Number.
80234-65-7Relevant articles and documents
A SIMPLE AND EFFICIENT SYNTHESIS OF (7E,9E,11Z,13E)-(5S,6R,15S)-TRIHYDROXYEICOSATETRAENOIC ACID (6R-LIPOXIN A)
Corey, E. J.,Su, Wei-guo,Cleaver, Martin B.
, p. 4181 - 4184 (2007/10/02)
A practical seven-step synthetic route to 6R-lipoxin A from arachidonic acid is described which makes this biologically interesting eicosanoid easily available.
