802566-87-6

Basic information

• Product Name: (R)-Ethyl 4-(1-aMinoethyl)benzate
• Synonyms: (R)-Ethyl 4-(1-aMinoethyl)benzate;ethyl 4-(1-aMinoethyl)benzoate
• CAS NO: 802566-87-6
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.2423
• Mol File: 802566-87-6.mol

Chemical Properties

• Boiling Point: 297.6±15.0 °C(Predicted)
• Appearance: /
• Density: 1.067±0.06 g/cm3(Predicted)
• PKA: 8.65±0.10(Predicted)
• CAS DataBase Reference: (R)-Ethyl 4-(1-aMinoethyl)benzate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-Ethyl 4-(1-aMinoethyl)benzate(802566-87-6)
• EPA Substance Registry System: (R)-Ethyl 4-(1-aMinoethyl)benzate(802566-87-6)

Safety Data

• Hazardous Substances Data: 802566-87-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-Ethyl 4-(1-aMinoethyl)benzate is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It plays a crucial role in the development of various medications, contributing to the advancement of healthcare and medical treatments.
Used in Research and Development:
(R)-Ethyl 4-(1-aMinoethyl)benzate is utilized as a reagent in organic synthesis within research and development laboratories. Its application in this field facilitates the exploration of new chemical reactions and the creation of novel organic compounds, furthering scientific knowledge and innovation.
Regulatory and Control Aspects:
Due to its potential hazardous properties, (R)-Ethyl 4-(1-aMinoethyl)benzate is subject to regulation and control. This ensures that its handling, storage, and usage adhere to safety standards, minimizing risks to both individuals and the environment.

Upstream product

• 142068-37-9 (S)-1-p-carboethoxyphenyl-1-(2-benzoylhydrazino)ethane 
• 38430-55-6 ethyl-4-acetylbenzoate 
• 142068-27-7 1-p-carboethoxyphenyl-1-(2-benzoylhydrazono)ethane 

Downstream Products

• 1429181-26-9 tert-butyl N-[(1S)-1-[4-(hydroxymethyl)phenyl]ethyl]carbamate 
• 1037252-32-6 [(S)-1-(4-formyl-phenyl)ethyl]carbamic acid tertbutyl ester 

Relevant articles and documents

Catalytic asymmetric reductive amination of ketones via highly enantioselective hydrogenation of the C=N double bond

We describe a convenient, chemoselective asymmetric reductive amination procedure for the conversion of ketones to chiral hydrazines and amines. The key step in the three-step process is enantioselective DuPHOS-Rh-catalyzed hydrogenation of the C=N double bond of N-acylhydrazones. Detailed optimization studies revealed the effect of solvent, temperature, and the N- acyl group on the enantioselectivity and catalytic efficiency of the reaction. The reduction products, N-acylhydrazines, were converted to hydrazines or amines through hydrolysis or treatment with samarium(II) iodide, respectively.