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Padmatin, a flavonoid derived from the plant Nelumbo nucifera, also known as the sacred lotus, is a naturally occurring compound with antioxidant properties. It possesses a range of potential medicinal benefits, including anti-inflammatory, anti-cancer, neuroprotective, antimicrobial, and anti-aging effects. Its natural origin makes Padmatin an attractive alternative to synthetic chemicals for various applications.

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  • 80453-44-7 Structure
  • Basic information

    1. Product Name: PadMatin
    2. Synonyms: PadMatin;Blumeatin C;Taxifolin 7-methyl ether
    3. CAS NO:80453-44-7
    4. Molecular Formula: C16H14O7
    5. Molecular Weight: 318.27816
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 80453-44-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 665.0±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.558±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 7.24±0.60(Predicted)
    10. CAS DataBase Reference: PadMatin(CAS DataBase Reference)
    11. NIST Chemistry Reference: PadMatin(80453-44-7)
    12. EPA Substance Registry System: PadMatin(80453-44-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 80453-44-7(Hazardous Substances Data)

80453-44-7 Usage

Uses

Used in Pharmaceutical Industry:
Padmatin is used as a medicinal compound for its anti-inflammatory, anti-cancer, and neuroprotective effects. Its natural antioxidant properties contribute to its potential applications in treating various health conditions.
Used in Cosmetic Industry:
Padmatin is used as an ingredient in cosmetic products for its antimicrobial and anti-aging properties. Its natural origin and potential benefits make it a desirable alternative to synthetic chemicals in skincare and beauty formulations.

Check Digit Verification of cas no

The CAS Registry Mumber 80453-44-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,4,5 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80453-44:
(7*8)+(6*0)+(5*4)+(4*5)+(3*3)+(2*4)+(1*4)=117
117 % 10 = 7
So 80453-44-7 is a valid CAS Registry Number.

80453-44-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-2,3-dihyd ro-4H-chromen-4-one

1.2 Other means of identification

Product number -
Other names taxifolin 7-methyl ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80453-44-7 SDS

80453-44-7Downstream Products

80453-44-7Relevant articles and documents

Structure-activity relationship for (+)-taxifolin isolated from silymarin as an inhibitor of amyloid β aggregation

Sato, Mizuho,Murakami, Kazuma,Uno, Mayumi,Ikubo, Haruko,Nakagawa, Yu,Katayama, Sumie,Akagi, Ken-Ichi,Irie, Kazuhiro

, p. 1100 - 1103 (2013/07/27)

Silymarin, the seed extract of Silybium marianum, has preventive effects against Alzheimer's disease-like pathogenesis in vivo. We isolated (+)-taxifolin (4) from silymarin as an inhibitor of aggregation of the 42- residue amyloid -protein. Structure-activity relationship studies revealed the 30,40-dihydroxyl groups to be critical to the anti-aggregative ability, whereas the 7-hydroxyl group and the stereochemistry at positions 2 and 3 were not important.

Methylation of Dihydroquercetin Acetates: Synthesis of 5-O-Methyldihydroquercetin

Kiehlmann, Eberhard,Slade, Peter W.

, p. 1562 - 1566 (2007/10/03)

The major products of methylation of dihydroquercetin (1, dhq) with diazomethane have been identified as 7-O-methyldhq (9), 7,3′ -di-O-methyldhq (10), 7,4′-di-O-methyldhq (11), and 7,3′,4′ -tri-O-methyldhq (2). With dhq 3,7,3′,4′-tetraacetate (6), dhq 3,5,3′,4′-tetraacetate (5), dhq 3,3′,4′-triacetate (7), dhq 7,3′,4′-triacetate (8), and dhq 3-acetate (4) the same reaction affords mainly 5-O-methyldhq 3,7,3′,4′-tetraacetate (15), 7-O-methyldhq 3,5,3′,4′-tetraacetate (13), 7-O-methyldhq 3,3′,4′-triacetate (14), 5-O-methyldhq 7,3′,4′ -triacetate (25), and 7-O-methyldhq 3-acetate (12), respectively. The methylation of 8 is accompanied by intermolecular acetyl migration from phenolic oxygen to the hydroxy group of the heterocyclic ring. 5-O-Methyldhq (28) is accessible by deacetylation of 25. 5,7-Di-O-methyldhq (29), four known methyl ethers, 13 new and three known methyl ether acetates of dhq, and six new isomers with 2,3-cis stereochemistry were spectroscopically identified.

7-O-METHYL-(2R:3R)-DIHYDROQUERCETIN 5-O-β-D-GLUCOSIDE AND OTHER FLAVONOIDS FROM PODOCARPUS NIVALIS

Markham, Kenneth R.,Webby, Rosemary F.,Vilain, Christian

, p. 2049 - 2052 (2007/10/02)

In the course of a chemotaxonomic survey of New Zealand Podocarpus species, a number of new flavonoid glycosides have been isolated from P. nivalis.These are: luteolin 3'-O-β-D-xyloside, luteolin 7-O-β-D-glucoside-3'-O-β-D-xyloside, dihydroquercetin 7-O-β-D-glucoside, 7-O-methyl-(2R:3R)-dihydrokaempferol 5-O-β-D-glucopyranoside, 7-O-methyl-(2R:3R)-dihydroquercetin 5-O-β-D-glucopyranoside, 7-O-methylkaempferol 5-O-β-D-glucopyranoside and 7-O-methylquercetin 5-O-β-D-glucopyranoside.Diagnostically useful physical techniques for distinguishing substitution patterns in dihydroflavonols are discussed and summarized.Glucosylation of the 5-hydroxyl group in (+)-dihydroflavonols is shown to reverse the sign of rotation at 589 nm.Key Word Index- Podocarpus nivalis; Podocarpaceae; snow totara; gymnosperm; flavonoid glycosides; 7-O-methyl-(2R:3R)-dihydroquercetin 5-O-β-D-glucoside; 7-O-methylquercetin 5-O-β-D-glucoside; luteolin 3'-O-β-D-xyloside; luteolin 7-O-β-D-glucoside-3'-O-β-D-xyloside; FAB-MS; 13C NMR.

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