805251-34-7Relevant articles and documents
TRI-SUBSTITUED 2-BENZHYDRYL-5-BENZLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES
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Page/Page column 17-18; Sheet 1, (2008/06/13)
Novel 3,6-disubstituted pyrans, optionally with a further substituent at the 4-position, are monoamine reuptake inhibitors with activity profiles of anti- depressants.
Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters
Zhang, Shijun,Zhen, Juan,Reith, Maarten E.A.,Dutta, Aloke K.
, p. 6301 - 6315 (2007/10/03)
Structure-activity relationship study of cis-(6-benzhydryl-tetrahydropyran- 3-yl)-(4-fluorobenzyl)-amine derivatives and their bioisosteric analogs for the monoamine transporters in the central nervous system. In our effort to delineate novel pharmacophor