Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus
Chikungunya virus (CHIKV) is a re-emerging vector-borne alphavirus, and there is no approved effective antiviral treatment currently available for CHIKV. We previously reported the discovery of thieno[3,2-b]pyrrole 1b that displayed good antiviral activit
Ching, Kuan-Chieh,Tran, Thi Ngoc Quy,Amrun, Siti Naqiah,Kam, Yiu-Wing,Ng, Lisa F. P.,Chai, Christina L. L.
p. 3165 - 3186
(2017/04/21)
SYNTHESIS AND REACTIONS OF SUBSTITUTED FUROPYRROLE DERIVATIVES
Preparation of ethyl 2-methylfuropyrrole-5-carboxylate and 2-bromofuropyrrole-5-carboxylate, as well as alkylation and hydrolysis of ethyl 2-methylfuropyrrole-5-carboxylate, ethyl furopyrrole-5-carboxylate and ethyl (3,4-dichlo
Krutosikova, Alzbeta,Kovac, Jaroslav,Dandarova, Miloslava,Lesko, Jan,Ferik, Stefan
p. 2564 - 2573
(2007/10/02)
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