- PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
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Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-IR are also disclosed.
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Page/Page column 63
(2010/12/26)
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- a-AMINO ACID DERIVATIVE AND PHARMACEUTICAL COMPRISING THE SAME AS ACTIVE INGREDIENT
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The present invention provides novel α-amino acid derivatives of formula (1): (wherein, R1, R2, R3, R4, X and Y are as defined in the claims) or pharmaceutically acceptable salts, prodrugs or solvates thereof. T
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Page/Page column 47
(2009/04/23)
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- BENZO-SEPARATED PYRAZOLOPYRIMIDINES: EXPEDITIOUS SYNTHESES OF - AND -LINKED PYRAZOLOQUINAZOLINONES
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Syntheses for pyrazoloquinazolin-8(7H)-one (8) and its -analog 11 have been developed involving elaboration of aminoindazol-caboxylic acids 15 and 30 from correspondingly substituted methyl-nitroindazols, and subsequent anellation of the pyrimidine ring by v.Niementowski cyclization.
- Lichtenthaler, Frieder W.,Moser, Alfred
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p. 4397 - 4400
(2007/10/02)
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