81154-13-4Relevant articles and documents
Discovery and development of novel rhodanine derivatives targeting enoyl-acyl carrier protein reductase
Xu, Jian-Fei,Wang, Tian-Tian,Yuan, Qing,Duan, Yong-Tao,Xu, Yun-Jie,Lv, Peng-Cheng,Wang, Xiao-Ming,Yang, Yu-Shun,Zhu, Hai-Liang
, p. 1509 - 1516 (2019/03/05)
A series of rhodanine derivatives RB1–RB23 were synthesized through a two-round screening. Their Mycobacterial tuberculosis (Mtb) InhA inhibitory activity and Mtb growth blocking capability were evaluated. The most potent hit compound RB23 indicated compa
Microwave induced synthesis of the thiazolidine-2,4-dione motif and the efficient solvent free-solid phase parallel syntheses of 5-benzylidene- thiazolidine-2,4-dione and 5-benzylidene-2-thioxo-thiazolidine-4-one compounds
Kumar, B. R. Prashantha,Karvekar,Adhikary,Nanjan,Suresh
, p. 897 - 903 (2007/10/03)
Novel microwave induced method for the synthesis of thiazolidine-2,4-dione motif under solvent phase conditions is developed. Further we report an efficient, microwave assisted method for the parallel syntheses of biologically important 5-benzylidene-thiazolidine-2,4-dione and 5-benzylidene-2- thioxothiazolidine-4-one compounds under solid-phase and solvent-free conditions. A comparative study between the developed microwave methods and the conventional methods is described. We have also illustrated the possible mechanism behind to address the reason why piperidine, acetic acid and silica gel enhanced the Knoevenagel condensation reaction.
Method for treating multiple sclerosis
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, (2008/06/13)
Provided is a method of treating multiple sclerosis employing certain aryl-substituted rhodanines.
COMPOUNDS USEFUL AS HYPOGLYCEMIC AGENTS AND FOR TREATING ALZHEIMER'S DISEASE
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, (2008/06/13)
Provided are methods for treating hyperglycemia and Alzheimer's disease utilizing certain rhodanine derivatives. Certain of the rhodanine derivatives utilized in the instant methods are novel and, accordingly, such compounds and pharmaceutical formulation
Aryl-substituted rhodanine derivatives
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, (2008/06/13)
Provided are certain aryl-substituted rhodanine derivatives, treatment methods and pharmaceutical formulations thereof.
Method of treating type I diabetes
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, (2008/06/13)
Provided is a method for treating Type I diabetes in mammals utilizing certain aryl-substituted rhodanine derivatives.