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SEGLITIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (2s)-6-amino-2-[[(2r)-2-[[(2s)-3-(4-hydroxyphenyl)-2-[[(2s)-2-(methylideneamino)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-y

    Cas No: 81377-02-8

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  • 1 Kilogram

  • 100 Kilogram/Week

  • Career Henan Chemical Co
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  • 81377-02-8 Structure
  • Basic information

    1. Product Name: SEGLITIDE
    2. Synonyms: SEGLITIDE;MK 678;CYCLIC(N-METHYL-ALA-TYR-D-TRP-LYS-VAL-PHE);Cyclic(N-methyl-Ala-Tyr-D-Trp-Lys-Val-Phe), MK 678;M.W. 808.98 C44H56N8O7;Cyclo(L-Tyr-D-Trp-L-Lys-L-Val-L-Phe-N-methyl-L-Ala-);L-363586;N-Methyl-cyclo(L-Ala-L-Tyr-D-Trp-L-Lys-L-Val-L-Phe-)
    3. CAS NO:81377-02-8
    4. Molecular Formula: C44H56N8O7
    5. Molecular Weight: 808.96
    6. EINECS: N/A
    7. Product Categories: Somatostatin receptor
    8. Mol File: 81377-02-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 1194.3±65.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: white/solid
    5. Density: 1.186±0.06 g/cm3(Predicted)
    6. Refractive Index: 1.569
    7. Storage Temp.: 2-8°C
    8. Solubility: H2O: 26 mg/mL, soluble
    9. PKA: pKa 9.7(H2O) (Uncertain)
    10. CAS DataBase Reference: SEGLITIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: SEGLITIDE(81377-02-8)
    12. EPA Substance Registry System: SEGLITIDE(81377-02-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 81377-02-8(Hazardous Substances Data)

81377-02-8 Usage

Uses

Different sources of media describe the Uses of 81377-02-8 differently. You can refer to the following data:
1. Antidiabetic.
2. Seglitide is a somatostatin (SST) agonist.

Check Digit Verification of cas no

The CAS Registry Mumber 81377-02-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 81377-02:
(7*8)+(6*1)+(5*3)+(4*7)+(3*7)+(2*0)+(1*2)=128
128 % 10 = 8
So 81377-02-8 is a valid CAS Registry Number.
InChI:InChI=1/C44H56N8O7/c1-26(2)38-43(58)50-37(23-28-12-6-5-7-13-28)44(59)52(4)27(3)39(54)48-35(22-29-17-19-31(53)20-18-29)41(56)49-36(24-30-25-46-33-15-9-8-14-32(30)33)42(57)47-34(40(55)51-38)16-10-11-21-45/h5-9,12-15,17-20,25-27,34-38,46,53H,10-11,16,21-24,45H2,1-4H3,(H,47,57)(H,48,54)(H,49,56)(H,50,58)(H,51,55)/t27-,34-,35-,36+,37-,38-/m0/s1

81377-02-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-2-(methylideneamino)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-3-methyl-1-oxo-1-[[(2S)-1-oxo-3-phenylpropan-2-yl]amino]butan-2-yl]hexanamide

1.2 Other means of identification

Product number -
Other names Seglitida

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81377-02-8 SDS

81377-02-8Downstream Products

81377-02-8Relevant articles and documents

Solid phase synthesis of 'head-to-tail' cyclic peptides using a sulfonamide 'safety-catch' linker: The cleavage by cyclization approach

Yang, Lihu,Morriello, Greg

, p. 8197 - 8200 (2007/10/03)

A new approach to the synthesis of cyclic peptides using Kenner's 'safety-catch' sulfonamide linker is described. After the linear peptide is assembled by Fmoc peptide synthesis, trityl is adopted as a temporary protecting group for the N-terminus amine while activating the acyl sulfonamide linker. Head-to-tail cyclization-cleavage of the amine to the acyl sulfonamide ensured final product purity.

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