SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS
Certain substituted phenyl propyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
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Page/Page column 51
(2008/12/05)
Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activity
The synthesis and structure-activity relationships of a series of novel phenoxyphenyl diamine derivatives with affinity for both the histamine H3 receptor and the serotonin transporter is described.
Stocking, Emily M.,Miller, Jennifer M.,Barbier, Ann J.,Wilson, Sandy J.,Boggs, Jamin D.,McAllister, Heather M.,Wu, Jiejun,Lovenberg, Timothy W.,Carruthers, Nicholas I.,Wolin, Ronald L.
p. 3130 - 3135
(2008/02/13)
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