819867-24-8

Basic information

• Product Name: (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine
• Synonyms: (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine;(2',6'-Dimethoxy-[1,1'-biphenyl]-2-yl)
• CAS NO: 819867-24-8
• Molecular Formula: C26H23O2P
• Molecular Weight: 398.433381
• Mol File: 819867-24-8.mol

Chemical Properties

• Melting Point: 138 °C(Solv: acetone (67-64-1))
• Boiling Point: 487.0±35.0 °C(Predicted)
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine(CAS DataBase Reference)
• NIST Chemistry Reference: (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine(819867-24-8)
• EPA Substance Registry System: (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine(819867-24-8)

Safety Data

• Hazardous Substances Data: 819867-24-8(Hazardous Substances Data)

Usage

Uses

Used in Organometallic Chemistry:
(2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine is used as a ligand for the formation of transition metal complexes. Its electron-donating methoxy groups and the diphenylphosphine moiety contribute to the stability and reactivity of these complexes, facilitating various chemical reactions.
Used in Catalysis:
In the field of catalysis, (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine is employed as a ligand to improve the efficiency and selectivity of catalytic reactions. Its ability to coordinate with metal centers allows for the development of catalysts that can effectively promote a wide range of chemical transformations.
Used in Pharmaceutical Industry:
(2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine is used as a building block for the synthesis of pharmaceutical compounds. Its unique structure and reactivity enable the creation of novel drug candidates with potential therapeutic applications.
Used in Material Science:
In material science, (2',6'-DiMethoxy-[1,1'-biphenyl]-2-yl)diphenylphosphine is utilized in the development of advanced materials with specific properties. Its coordination chemistry with metal centers can lead to the formation of materials with tailored characteristics for various applications, such as sensors, optoelectronics, and energy storage devices.

Upstream product

• 880127-77-5 diphenyl 2-(2',6'-dimethoxybiphenylyl)phosphonite 
• 591-51-5 phenyllithium 
• 101-02-0 triphenyl phosphite 
• 755017-61-9 2'-bromo-2,6-dimethoxybiphenyl 

Relevant articles and documents

Evaluation of electron-deficient phosphine ligands for direct arylation of heterocycles

New electron-deficient biarylphosphine ligands were studied and proved to be efficient for the direct arylation of heteroarenes with aryl iodides. The ability of a more electron-deficient palladium centre to accelerate the arylation of heterocycles that remained unreactive with aryl iodides in the past has been validated and these heteroarenes can now be smoothly reacted in the presence of a new electrophilic catalyst. Experimental evidence suggests a viable concerted metalation-deprotonation pathway for the C-H bond cleavage step with an electron-deficient palladium centre.

One-pot syntheses of sterically shielded phosphorus ligands by selective stepwise nucleophilic substitution at triphenyl phosphite

A general, chlorophosphine-free procedure for the preparation of phosphonites, phosphinites and tertiary phosphines with at least one sterically demanding substituent has been developed. In this modular methodology, successive addition of stoichiometric a