- SINTESI ED ATTIVITA ANTIMICOTICA DI DERIVATI DELL'1,3,4-TIADIAZOLOPIRIMIDONE
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As a continuation of previous research designed to obtain derivatives of 1,3,4-thiadiazole of pharmacological interest, some derivatives of 1,3,4-thiadiazolepyrimidin-5-one and isomeric 7-one were prepared.The fungistatic activity of the products was tested in vitro against the following: Candida albicans, Candida parapsilosis, Candida tropicalis, Cryptococcus neoformans and Trichophyton rubrum.No relevant antifungal activity was observed for any of the compounds examined.
- Russo, F.,Santagati, M.,Santagati, A.,Blandino, G.
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p. 983 - 993
(2007/10/02)
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