- REACTIONS OF 4-ARYL-1-METHOXYNAPHTHALENE-2,3-DICARBOXYLIC ACID ANHYDRIDES AND NAPHTHO(2,3-c)FURAN-1-(3H)-ONE DERIVATIVES WITH HYDRAZINES
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Reactions of anhydrides of 4-aryl-1-methoxynaphthalene-2,3-dicarboxylic acids, Ia and Ib, with hydrazine hydrate gave derivatives of benzo(g)phthalazine, IV-VI.Analogous reactions of the compounds Ia and Ib with hydrazines IIIa and IIIb afforded the corresponding N-aminoimides, VII-X.Derivatives of naphtho(2,3-c)furan-1(3H)-one, IIa-IIc, reacted with hydrazine hydrate with the formation of benzo(f)isoindoline-1(3H)-one derivatives, XI-XIII.In the antineoplastic screening the tested compounds have not proved efficacious.
- Krepelka, Jiri,Vancurova, Iva,Holubek, Jiri
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p. 1252 - 1257
(2007/10/02)
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