823804-66-6Relevant articles and documents
Resveratrol derivative and application thereof
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Paragraph 0041-0044, (2020/12/30)
The invention provides a resveratrol derivative shown as a formula (II), in the formula (II), when R1 is hydroxyl, halogen, C1-C4 alkyl or C1-C4 methoxy, R2 is H; when R1 is H, R2 is halogen; and particularly, when R1 is hydroxyl, halogen, C1-C4 alkyl or C1-C4 methoxy, R2 is H preferably. According to the new compound resveratrol derivative and the preparation method thereof, the operation processis simple, raw material sources are commercialized and easy to obtain, and compared with resveratrol and 7-hydroxy coumarin, the inhibition effect is remarkably improved. Compared with the previous resveratrol modification method, the method has the advantages that the reaction is completed in one step, and is more direct, efficient and rapid.
A facile and rapid access to resveratrol derivatives and their radioprotective activity
Uzura, Saori,Sekine-Suzuki, Emiko,Nakanishi, Ikuo,Sonoda, Motohiro,Tanimori, Shinji
, p. 3886 - 3891 (2016/08/01)
A facile and rapid access to resveratrol derivatives has been achieved based on palladium-catalyzed oxidative Heck reaction of aryl boronic acids with styrenes followed by demethylation in moderate to good yields. A series of resveratrol derivatives with various functional groups has been synthesized easily. The radioprotective activity of synthesized compounds has also been evaluated using rat thymocytes. The results revealed that some resveratrol derivatives efficiently protected the thymocytes from radiation-induced apoptosis.
