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1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea is a potent chemical compound that belongs to the nitrosourea family, characterized by its strong anticancer properties. As a DNA alkylating agent, it forms covalent bonds with the nucleobases in DNA, causing DNA damage and cell death. 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea is known for its effectiveness against various types of cancer, although it comes with significant side effects and requires careful medical supervision.

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  • 82498-58-6 Structure
  • Basic information

    1. Product Name: 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea
    2. Synonyms:
    3. CAS NO:82498-58-6
    4. Molecular Formula: C10H15ClN4O2
    5. Molecular Weight: 258.7047
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 82498-58-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.35g/cm3
    6. Refractive Index: 1.593
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea(82498-58-6)
    11. EPA Substance Registry System: 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea(82498-58-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 82498-58-6(Hazardous Substances Data)

82498-58-6 Usage

Uses

Used in Anticancer Applications:
1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea is used as an anticancer agent for the treatment of brain tumors, melanoma, and lymphomas. It is effective due to its ability to cause DNA damage, which leads to cell death in cancerous cells. However, its use is accompanied by side effects such as myelosuppression, nausea, vomiting, and central nervous system toxicity, necessitating medical oversight.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea is used as a component in the development of cancer treatment drugs. Its potent DNA alkylating properties make it a valuable asset in the creation of medications aimed at combating cancer, despite the need for careful administration and management of its side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 82498-58-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,4,9 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 82498-58:
(7*8)+(6*2)+(5*4)+(4*9)+(3*8)+(2*5)+(1*8)=166
166 % 10 = 6
So 82498-58-6 is a valid CAS Registry Number.

82498-58-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(1-cyanocyclohexyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names Urea,N-(2-chloroethyl)-N'-(1-cyanocyclohexyl)-N-nitroso

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82498-58-6 SDS

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