The synthesis of an enantiomerically pure (5R,6R)-carbapenem 2 is described.The key step consists of a stereospecific C-C-coupling in 4-position of the lactam 9 by means of cuprates.
Koller,W,Linkies, A.,Pietsch, H.,Rehling, H.,Reuschling, D.
p. 1545 - 1548
(2007/10/02)
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