- Rhodium-Catalyzed Remote Isomerization of Alkenyl Alcohols to Ketones
-
We develop herein an efficient rhodium-catalyzed remote isomerization of aromatic and aliphatic alkenyl alcohols into ketones. This catalytic process, with a commercially available catalyst and ligand ([RhCl(cod)]2 and Xantphos), features high efficiency, low catalyst loading, good functional group tolerance, a broad substrate scope, and no (sub)stoichiometric additive. Preliminary mechanistic studies suggest that this transformation involves an iterative dissociative β-hydride elimination-migration insertion process.
- Dong, Wenke,Yang, Hongxuan,Yang, Wen,Zhao, Wanxiang
-
supporting information
(2020/02/28)
-
- Nickel-catalyzed homoallylation reaction of aldehydes with 1,3-dienes: Stereochemical and mechanistic studies
-
(Matrix presented) Contrary to what was reported, the coupling reaction of nickel-catalyzed cyclic diene such as cyclohexadiene with carbonyl compounds in the presence of diethyl zinc afforded γ,δ-alkenyl alcohols in good yields.
- Loh, Teck-Peng,Song, Hong-Yan,Zhou, Yan
-
p. 2715 - 2717
(2007/10/03)
-