- Benzo[b]thiophenes
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Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
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- Synthesis of (dihydrobenzoxathiinyloxy)acetic acids
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Several (dihydrobenzoxathiinyloxy)acetic acids have been prepared as potential antihypertensive agents. The dihydrobenzoxathiin ring system was constructed via an intramolecular alkoxide displacement reaction.
- Tegeler,Ong,Profitt
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p. 867 - 870
(2007/10/02)
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- Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich bases
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Described are compounds of the formula STR1 wherein R is hydrogen, loweralkyl, aminomethyl or halo; R1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH2, Sulfur or a single bond; X is oxygen, CH2, sulfur or sulfoxide; and Y is hydrogen, loweralkyl or halo and may be the same or different, and pharmaceutically acceptable salts thereof. The compounds are effective as diuretic agents.
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