Synthesis and Pharmacological Characterization in Vitro of Cyclic Enkephalin Analogues: Effect of Conformational Constraints on Opiate Receptor Selectivity
Using a combination of solid-phase and solution methods, we synthesized a series of cyclic 5> enkephalin analogues by substitution of D-α,ω-diamino acids in position 2 of the enkephalin sequence and cyclization of the ω-amino group to the C
DiMaio, John,Nguyen, Thi M.-D.,Lemieux, Carole,Schiller, Peter W.
p. 1432 - 1438
(2007/10/02)
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