- SYNTHESIS OF OCTYL β-D-GLUCOPYRANOSIDE-AMINOBUTYRIC (GABA) AND AMINOHYDROXYBUTYRIC (GABOB) CONJUGATES
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The syntheses of octyl β-D-glucopyranoside-GABA and GABOB conjugates are presented.The selectively protected octyl-β-D-glucopyranoside and γ-aminobutyric acids, were coupled with N,N'-dicyclohexylcarbodiimide. 1H and 13C NMR spectroscopy were used to verify the proposed structures.
- Gastaldi, G.,Focher, B.,Guerrini, M.,Alonso, D.
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p. 1009 - 1024
(2007/10/02)
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- Absolute configuration of main chain of AAL-toxins
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AAL-toxins TA1 1 and TA2 2, host-specific toxins produced by Alternaria alternata, were degraded to 2-methylbutanol, 3-methylnonan-1,9-diol and N-protected 4-aminobutan-1,3-diol, which were further converted to (R)-MTPA esters. These esters were correlated with synthetic samples by comparison of their 500 MHz 1H-NMR spectra. The remaining stereocenters were determined by the comparison of 1H-NMR spectra of 6a and 7 derived from 1 and 2 with those of synthetic model compounds. These data conclude that AAL-toxins possess 2S, 4S, 5R, 11S, 13S, 14R and 15R configurations.
- Oikawa, Hideaki,Matsuda, Isamu,Kagawa, Takashi,Ichihara, Akitami,Kohmoto, Keisuke
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p. 13347 - 13368
(2007/10/02)
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