A simple and highly efficient synthesis of N-phenyl-2-polyfluoroalkyl-4-quinolones from 2-anilinoacetophenone and RFCO2Et
The condensation of 2-anilinoacetophenone with RFCO2Et (RF = CF2H, CF3, C2F5) in the presence of LiH in THF affords the corresponding N -phenyl-2-polyfluoroalkyl-4-quinolones in