Synthesis of novel highly functionalized 4-thiazolidinone derivatives from 4-phenyl-3-thiosemicarbazones
We present herein the synthesis in good yields of two series of highly functionalized thiazolidinone derivatives from the reactions of various 4-phenyl-3-thio-semicarbazones with ethyl 2-bromoacetate and diethyl acetylenedicarboxylate, respectively.
One-pot synthesis and anticancer studies of 2-arylamino-5-aryl-1,3,4- thiadiazoles
A series of 2-arylamino-5-aryl-1,3,4-thiadiazoles 1a-j were synthesized and screened for their anticancer activity against various human cancer cell lines. The novel one-pot synthesis of 1,3,4-thiadiazoles was achieved by refluxing aryl aldehydes, hydrazi
Synthesis, anti-Toxoplasma gondii and antimicrobial activities of benzaldehyde 4-phenyl-3-thiosemicarbazones and 2-[(phenylmethylene)hydrazono]-4-oxo-3-phenyl-5-thiazolidineacetic acids
In the present communication, a new series of 2-[(phenylmethylene)hydrazono]-4-oxo-3-phenyl-5-thiazolidineacetic acids (2a-p) have been synthesized. Benzaldehyde 4-phenyl-3-thiosemicarbazones substituted (1a-p) were also obtained and used as intermediate
de Aquino, Thiago M.,Liesen, Andre P.,da Silva, Rosa E.A.,Lima, Vania T.,Carvalho, Cristiane S.,de Faria, Antonio R.,de Araujo, Janete M.,de Lima, Jose G.,Alves, Antonio J.,de Melo, Edesio J.T.,Goes, Alexandre J.S.
p. 446 - 456
(2008/09/17)
Acylation and carbamoylation of 2-hydrazinothiazole derivatives. Identification of isomeric structures
Acylation and carbamoylation of 2-(arylmethylidenehydrazino)- and 2-(aroylhydrazino)thiazoles was performed, and structure of the products was established.