842169-71-5 Usage
Uses
Used in Pharmaceutical Research:
1-(3-Bromo-phenyl)-2,2,2-trifluoro-ethylamine hydrochloride is used as a key intermediate in the synthesis of various drugs, leveraging its unique structural features to contribute to the development of new therapeutic agents with potential applications across different medical fields.
Used in Organic Synthesis:
In the realm of organic synthesis, 1-(3-Bromo-phenyl)-2,2,2-trifluoro-ethylamine hydrochloride serves as a valuable precursor for the creation of biologically active molecules, facilitating the design and production of innovative compounds with specific pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 842169-71-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,2,1,6 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 842169-71:
(8*8)+(7*4)+(6*2)+(5*1)+(4*6)+(3*9)+(2*7)+(1*1)=175
175 % 10 = 5
So 842169-71-5 is a valid CAS Registry Number.
842169-71-5Relevant articles and documents
Synthesis of alpha fluoroalkyl amines
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Page/Page column 8; 9, (2008/06/13)
This invention describes the reaction of an alpha fluoroalkyl ketone with a bis(trialkylsilyl)amide to give a stable N-trialkylsilyl imine. Treatment of the N-trialkylsilyl imine with an alcohol leads to solvolysis of the trialkylsilyl group and yields a
Unprecedented catalytic asymmetric reduction of N-H imines
Gosselin, Francis,O'Shea, Paul D.,Roy, Stephanie,Reamer, Robert A.,Chen, Cheng-Yi,Volante, Ralph P.
, p. 355 - 358 (2007/10/03)
(Chemical Equation Presented) Addition of lithium bis(trimethylsilyl)amide to perfluorinated ketones 1a-j affords (E)-N-TMS-ketimines 2a-j that are reduced in situ to afford racemic perfluoromethylated amine hydrochloride salts 3a-j in 54-97% yields. Solv