Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate, with the CAS number 84428-15-9, is an off-white solid compound that is useful in organic synthesis. It is characterized by its unique chemical structure, which includes a hydroxy and methoxy substituent on a phenyl ring, and an ester functional group.

84428-15-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 84428-15-9 Structure
  • Basic information

    1. Product Name: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate
    2. Synonyms: 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoic Acid Ethyl Ester;Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate
    3. CAS NO:84428-15-9
    4. Molecular Formula: C12H14O4
    5. Molecular Weight: 222.23716
    6. EINECS: N/A
    7. Product Categories: Aromatics
    8. Mol File: 84428-15-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
    9. CAS DataBase Reference: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(84428-15-9)
    11. EPA Substance Registry System: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(84428-15-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84428-15-9(Hazardous Substances Data)

84428-15-9 Usage

Uses

Used in Organic Synthesis:
Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate is used as a synthetic intermediate for the production of various organic compounds. Its unique chemical structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate is used as a key intermediate in the synthesis of pharmaceutical compounds. Its presence in the molecule can impart specific biological activities, making it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique structure can contribute to the effectiveness of these products in controlling pests and weeds.
Used in Specialty Chemicals:
Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate is used as a raw material in the production of specialty chemicals, such as dyes, fragrances, and flavorings. Its chemical properties can be utilized to create unique and desirable characteristics in these products.

Check Digit Verification of cas no

The CAS Registry Mumber 84428-15-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,2 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 84428-15:
(7*8)+(6*4)+(5*4)+(4*2)+(3*8)+(2*1)+(1*5)=139
139 % 10 = 9
So 84428-15-9 is a valid CAS Registry Number.

84428-15-9Relevant articles and documents

Hypervalent-Iodine(III)-Mediated Tandem Oxidative Dearomatization/Aziridination of Phenolic Amines: Synthesis of Functionalized Unactivated Aziridines

Cao, Ye-Xing,Silalai, Patamawadee,Liu, Chun-Fang,Yu, Ke-Yin,Bao, Xu,Zhao, Xian-He,Saeeng, Rungnapha,Fan, Chun-An

supporting information, p. 8473 - 8478 (2021/05/17)

A new hypervalent-iodine(III)-mediated tandem reaction involving oxidative dearomatization and in situ aziridination of phenolic amines is described, providing a mild and effective method for the assembly of structurally interesting and synthetically usef

Preparation method of neoflavonoids

-

, (2017/04/26)

The invention relates to the field of chemical synthesis, in particular to a preparation method of neoflavonoids. The preparation method is characterized by comprising the following steps of using substituted benzaldehyde as an initial raw material to be reacted with malonic acid to generate a substituted phenylacrylic acid compound; performing an addition reaction, an elimination reaction and the like on the substituted phenylacrylic acid compound, or performing acetylation so as to protect a phenolic hydroxyl group, then performing a bromination reaction and the elimination reaction so as to synthesize the substituted phenylpropiolic acid compound ; and using montmorillonite K-10 after being acidulated by sulfuric acid as a catalyst, enabling the substituted phenylpropiolic acid compound and a phenolic compound to perform a heating reaction so as to generate the neoflavonoids. Compared with the prior art, the preparation method of the neoflavonoids, disclosed by the invention, has the characteristics that raw materials are cheap, and easy to obtain, the operation is simple, the catalyst can be recovered for use, and the method is environmentally-friendly, the post-treatment is simple, and the production cost is low, and the method has a high popularization and application value.

Synthesis and anticancer activities of glycyrrhetinic acid derivatives

Li, Yang,Feng, Ling,Song, Zhi-Fang,Li, Hai-Bei,Huai, Qi-Yong

, (2016/05/09)

A total of forty novel glycyrrhetinic acid (GA) derivatives were designed and synthesized. The cytotoxic activity of the novel compounds was tested against two human breast cancer cell lines (MCF-7, MDA-MB-231) in vitro by the MTT method. The evaluation results revealed that, in comparison with GA, compound 42 shows the most promising anticancer activity (IC50 1.88 ± 0.20 and 1.37 ± 0.18 μM for MCF-7 and MDA-MB-231, respectively) and merits further exploration as a new anticancer agent.

On the origin of the methyl radical loss from deprotonated ferulic and isoferulic acids: Electronic excitation of a transient structure

Zhang, Xiaoping,Li, Fei,Lv, Huiqing,Wu, Yanqing,Bian, Gaofeng,Jiang, Kezhi

, p. 941 - 948 (2013/07/19)

Formation of radical fragments from even-electron ions is an exception to the "even-electron rule". In this work, ferulic acid (FA) and isoferulic acid (IFA) were used as the model compounds to probe the fragmentation mechanisms and the isomeric effects o

Synthesis of some phenylpropanoid glycosides (PPGs) and their acetylcholinesterase/xanthine oxidase inhibitory activities

Li, Xiao-Dong,Kang, Shuai-Tao,Li, Guo-Yu,Li, Xian,Wang, Jin-Hui

experimental part, p. 3580 - 3596 (2011/07/07)

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.

First synthesis, characterization, and evidence for the presence of hydroxycinnamic acid sulfate and glucuronide conjugates in human biological fluids as a result of coffee consumption

Fumeaux, Rene,Menozzi-Smarrito, Candice,Stalmach, Angelique,Munari, Caroline,Kraehenbuehl, Karin,Steiling, Heike,Crozier, Alan,Williamson, Gary,Barron, Denis

supporting information; experimental part, p. 5199 - 5211 (2010/12/25)

A systematic investigation of the human metabolism of hydroxycinnamic acid conjugates was carried out. A set of 24 potential human metabolites of coffee polyphenols has been chemically prepared, and used as analytical standards for unequivocal identifications. These included glucuronide conjugates and sulfate esters of caffeic, ferulic, isoferulic, m-coumaric and p-coumaric acids as well as their dihydro derivatives. A particular focus has been made on caffeic and 3,4-dihydroxyphenylpropionic acid derivatives, especially the sulfate conjugates, for which regioselective preparation was particularly challenging, and have so far never been identified as human metabolites. Ten out of the 24 synthesized conjugates have been identified in human plasma and/or urine after coffee consumption. A number of these conjugates were synthesized, characterized and detected as hydroxycinnamic acid metabolites for the first time. This was the case of dihydroisoferulic acid 3′-O-glucuronide, caffeic acid 3′-sulfate, as well as the sulfate and glucuronide derivatives of 3,4-dihydroxyphenylpropionic acid.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 84428-15-9