- Sulfonamide as Photoinduced Hydrogen-Atom Transfer Catalyst for Regioselective Alkylation of C(sp3)-H Bonds Adjacent to Heteroatoms
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Based on the DFT calculations, the sulfonamide was explored as an efficient hydrogen-atom transfer catalyst for the C(sp3)-H alkylation. The combination of a metal-free photoredox catalyst and a sulfonamide catalyst enables highly regioselective alkylation of the C-H bonds adjacent to heteroatoms, which features broad substrate scope and excellent functional group compatibility. Remarkably, the sulfonamide catalyst was also applicable to the C(sp3)-C(sp3) couplings through the merger of photoredox, nickel, and HAT catalysis.
- Ma, Zhi-Yong,Li, Mengyang,Guo, Li-Na,Liu, Le,Wang, Dongdong,Duan, Xin-Hua
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supporting information
p. 474 - 479
(2021/01/13)
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- Eosin Y as a Direct Hydrogen-Atom Transfer Photocatalyst for the Functionalization of C?H Bonds
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Eosin Y, a well-known economical alternative to metal catalysts in visible-light-driven single-electron transfer-based organic transformations, can behave as an effective direct hydrogen-atom transfer catalyst for C?H activation. Using the alkylation of C?H bonds with electron-deficient alkenes as a model study revealed an extremely broad substrate scope, enabling easy access to a variety of important synthons. This eosin Y-based photocatalytic hydrogen-atom transfer strategy is promising for diverse functionalization of a wide range of native C?H bonds in a green and sustainable manner.
- Fan, Xuan-Zi,Rong, Jia-Wei,Wu, Hao-Lin,Zhou, Quan,Deng, Hong-Ping,Da Tan, Jin,Xue, Cheng-Wen,Wu, Li-Zhu,Tao, Hai-Rong,Wu, Jie
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supporting information
p. 8514 - 8518
(2018/07/14)
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- Vinylpyridines as Building Blocks for the Photocatalyzed Synthesis of Alkylpyridines
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The photocatalyzed addition of several hydrogen donors (ethers, aldehydes, alkanes, amides) onto vinylpyridines was achieved. This approach provided access to alkylpyridines, which are important building blocks for the preparation of compounds with biological activity. The strategy was very simple and straightforward because it required only a small amount of a cheap decatungstate salt as photocatalyst. As an added advantage, the reaction could be performed under sunlight irradiation as well as under flow conditions.
- Capaldo, Luca,Fagnoni, Maurizio,Ravelli, Davide
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supporting information
p. 6527 - 6530
(2017/05/15)
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