845264-90-6

Basic information

• Product Name: 3,4-DIHYDRO-1(2H)-QUINOLINEACETIC ACID
• Synonyms: 3,4-DIHYDRO-1(2H)-QUINOLINEACETIC ACID
• CAS NO: 845264-90-6
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Product Categories: pharmacetical
• Mol File: 845264-90-6.mol

Chemical Properties

• Boiling Point: 384.7°C at 760 mmHg
• Flash Point: 186.5°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 1.32E-06mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 3,4-DIHYDRO-1(2H)-QUINOLINEACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-1(2H)-QUINOLINEACETIC ACID(845264-90-6)
• EPA Substance Registry System: 3,4-DIHYDRO-1(2H)-QUINOLINEACETIC ACID(845264-90-6)

Safety Data

• Hazardous Substances Data: 845264-90-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13NO2/c13-11(14)8-12-7-3-5-9-4-1-2-6-10(9)12/h1-2,4,6H,3,5,7-8H2,(H,13,14)

Upstream product

• 142978-20-9 (3,4-dihydro-2H-quinolin-1-yl)-acetic acid ethyl ester 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 1321615-76-2 2-(4-nitrophenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321615-75-1 2-(4-chlorophenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321615-74-0 2-(4-methylphenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321615-73-9 2-phenylcarbonylmethylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-14-1 5-ethyl-2-(4-fluorobenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-13-0 5-ethyl-2-(4-methoxybenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-12-9 5-ethyl-2-(4-cyanobenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-11-8 5-ethyl-2-(4-nitrobenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-10-7 5-ethyl-2-(4-chlorobenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl) pyrimidin-4(3H)-one 
• 1321616-09-4 5-ethyl-2-(4-methylbenzylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-08-3 5-ethyl-2-benzylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-07-2 5-ethyl-2-(4-fluorophenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-06-1 5-ethyl-2-(4-methoxylphenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 
• 1321616-05-0 5-ethyl-2-(4-cyanophenylcarbonylmethylthio)-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-one 

Relevant articles and documents

4-(Benzoimidazol-2-yl)-thiazole Compounds and Related Aza Derivatives

The invention relates to compounds of Formula (I) wherein ring A, X, (R1)n, R2, R3, R4, R4′, R5, n, and p are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as modulators of the CXCR3 receptor.

4-(BENZOIMIDAZOL-2-YL)-THIAZOLE COMPOUNDS AND RELATED AZA DERIVATIVES

The invention relates to compounds of Formula (I) wherein ring A, X, (R1)n, R2, R3, R4, R4', R5, n, and p are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as modulators of the CXCR3 receptor.

Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4- dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

A series of novel S-DABO analogues of 5-alkyl-2-arylthio-6-((3,4- dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones were synthesized and evaluated as inhibitors of human immunodeficiency virus type-1 (HIV-1). Among them, the most potent HIV-1 inhibitor