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CAS

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845885-80-5

5-(4-Cyanophenyl)nicotinic acid is a chemical compound with the molecular formula C13H8N2O2. It is a derivative of nicotinic acid and contains a 4-cyanophenyl group attached to the 5-position of the nicotinic acid molecule. 5-(4-CYANOPHENYL)NICOTINIC ACID is primarily used in pharmaceutical research and drug development, particularly in the study of nicotinic acid receptors and their potential as drug targets.

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  • 845885-80-5 Structure

  • Basic information

    1. Product Name: 5-(4-CYANOPHENYL)NICOTINIC ACID
    2. Synonyms: 5-(4-cyanophenyl)pyridine-3-carboxylic acid
    3. CAS NO:845885-80-5
    4. Molecular Formula: C13H8N2O2
    5. Molecular Weight: 224.218
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 845885-80-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(4-CYANOPHENYL)NICOTINIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(4-CYANOPHENYL)NICOTINIC ACID(845885-80-5)
    11. EPA Substance Registry System: 5-(4-CYANOPHENYL)NICOTINIC ACID(845885-80-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 845885-80-5(Hazardous Substances Data)

845885-80-5 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
5-(4-Cyanophenyl)nicotinic acid is used as a research compound for studying nicotinic acid receptors, which are potential drug targets for various therapeutic applications.
Used in Anti-Inflammatory Applications:
5-(4-Cyanophenyl)nicotinic acid is being investigated for its potential as an anti-inflammatory agent, which could be useful in the treatment of various inflammatory conditions.
Used in Metabolic and Cardiovascular Disease Treatment:
5-(4-Cyanophenyl)nicotinic acid is also being studied for its role in the treatment of metabolic and cardiovascular diseases, given its potential therapeutic effects in these areas.
Used in Preclinical Studies:
5-(4-Cyanophenyl)nicotinic acid has shown promise in preclinical studies, indicating its potential for future therapeutic applications in various medical fields.

Check Digit Verification of cas no

The CAS Registry Mumber 845885-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,8,8 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 845885-80:
(8*8)+(7*4)+(6*5)+(5*8)+(4*8)+(3*5)+(2*8)+(1*0)=225
225 % 10 = 5
So 845885-80-5 is a valid CAS Registry Number.

845885-80-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(4-cyanophenyl)pyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:845885-80-5 SDS

845885-80-5Downstream Products

845885-80-5Relevant articles and documents

Subtype-selective Nav1.8 sodium channel blockers: Identification of potent, orally active nicotinamide derivatives

Kort, Michael E.,Atkinson, Robert N.,Thomas, James B.,Drizin, Irene,Johnson, Matthew S.,Secrest, Matthew A.,Gregg, Robert J.,Scanio, Marc J.C.,Shi, Lei,Hakeem, Ahmed H.,Matulenko, Mark A.,Chapman, Mark L.,Krambis, Michael J.,Liu, Dong,Shieh, Char-Chang,Zhang, Xufeng,Simler, Gricelda,Mikusa, Joseph P.,Zhong, Chengmin,Joshi, Shailen,Honore, Prisca,Roeloffs, Rosemarie,Werness, Stephen,Antonio, Brett,Marsh, Kennan C.,Faltynek, Connie R.,Krafte, Douglas S.,Jarvis, Michael F.,Marron, Brian E.

scheme or table, p. 6812 - 6815 (2011/01/04)

A series of aryl-substituted nicotinamide derivatives with selective inhibitory activity against the Nav1.8 sodium channel is reported. Replacement of the furan nucleus and homologation of the anilide linker in subtype-selective blocker A-803467 (1) provided potent, selective derivatives with improved aqueous solubility and oral bioavailability. Representative compounds from this series displayed efficacy in rat models of inflammatory and neuropathic pain.

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