847264-30-6

Basic information

• Product Name: 3-(2-bromophenyl)Pyridine
• Synonyms: 3-(2-bromophenyl)Pyridine
• CAS NO: 847264-30-6
• Molecular Formula: C11H8BrN
• Molecular Weight: 234.09192
• Mol File: 847264-30-6.mol

Chemical Properties

• Boiling Point: 191°C/25mmHg(lit.)
• Appearance: /
• Density: 1.426±0.06 g/cm3(Predicted)
• Refractive Index: 1.6320 to 1.6360
• PKA: 4.20±0.12(Predicted)
• CAS DataBase Reference: 3-(2-bromophenyl)Pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-bromophenyl)Pyridine(847264-30-6)
• EPA Substance Registry System: 3-(2-bromophenyl)Pyridine(847264-30-6)

Safety Data

• Hazardous Substances Data: 847264-30-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(2-bromophenyl)Pyridine is used as a building block in organic synthesis for the development of potential drug candidates. It is valued for its ability to exhibit anti-cancer, anti-inflammatory, and antimicrobial properties, making it a promising compound for creating new medications.
Used in Electronic Materials Development:
3-(2-bromophenyl)Pyridine is also utilized in the research and development of various electronic materials. Its unique chemical structure lends itself to potential applications in this field, contributing to advancements in technology and material science.

Upstream product

• 244205-40-1 (2-bromophenyl)boronic acid 
• 626-55-1 3-Bromopyridine 
• 329214-79-1 3-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 583-53-9 2,3-dibromobenzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 1692-25-7 3-pyridylboronic acid 

Relevant articles and documents

Synthesis of Dibenzosiloles through Electrocatalytic Sila-Friedel-Crafts Reaction

A novel electrocatalyzed method for the preparation of dibenzosiloles was developed through intramolecular C?H/Si?H dehydrogenative coupling strategy starting from biarylhydrosilanes. Both electro-donating and electro-withdrawing substitution groups were tolerated for this transformation, and the desired dibenzosilole products could be obtained in moderate to excellent yields. A sila-Friedel-Crafts reaction mechanism was proposed on the basis of previous literature and our controlled experiments. (Figure presented.).

Transition-Metal-Free Heterobiaryl Synthesis via Aryne Coupling

We disclose, for the first time, an efficient route for the construction of various heterobiaryl backbones in fair to excellent yields using the Aryne coupling methodology. This study outlined the remarkable effect of external chelating ligands and salt additives on the heterocyclic partner reactivity in the aryne coupling reaction.

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF

Disclosed are a compound represented by chemical formula 1, an organic electric device comprising a first electrode, a second electrode, and an organic layer between the first electrode and the second electrode, and an electronic device including the same. By including the compound represented by the chemical formula 1 in the organic material layer, the driving voltage of the organic electric device can be lowered, and the luminous efficiency and lifespan can be improved.COPYRIGHT KIPO 2019

Experimental and Computational Exploration of para-Selective Silylation with a Hydrogen-Bonded Template

The regioselective conversion of C?H bonds into C?Si bonds is extremely important owing to the natural abundance and non-toxicity of silicon. Classical silylation reactions often suffer from poor functional group compatibility, low atom economy, and insufficient regioselectivity. Herein, we disclose a template-assisted method for the regioselective para silylation of toluene derivatives. A new template was designed, and the origin of selectivity was analyzed experimentally and computationally. An interesting substrate–solvent hydrogen-bonding interaction was observed. Kinetic, spectroscopic, and computational studies shed light on the reaction mechanism. The synthetic significance of this strategy was highlighted by the generation of a precursor of a potential lipophilic bioisostere of γ-aminobutyric acid (GABA), various late-stage diversifications, and by mimicking enzymatic transformations.