847902-56-1

Basic information

• Product Name: 5-fluoro-2-nitropyridin-3-ol
• Synonyms: 5-fluoro-2-nitropyridin-3-ol
• CAS NO: 847902-56-1
• Molecular Formula: C5H3FN2O3
• Molecular Weight: 158.0873232
• Mol File: 847902-56-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 5-fluoro-2-nitropyridin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-2-nitropyridin-3-ol(847902-56-1)
• EPA Substance Registry System: 5-fluoro-2-nitropyridin-3-ol(847902-56-1)

Safety Data

• Hazardous Substances Data: 847902-56-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Fluoro-2-nitropyridin-3-ol is utilized as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of a variety of medicinal compounds, making it a valuable asset in drug discovery and design.
Used in Agrochemical Synthesis:
In the agrochemical sector, 5-fluoro-2-nitropyridin-3-ol is employed as an intermediate for the production of various agrochemicals. Its incorporation aids in the development of compounds that can be used in crop protection and other agricultural applications, enhancing the industry's ability to combat pests and diseases.
Used in Organic Synthesis:
5-Fluoro-2-nitropyridin-3-ol is also used in organic synthesis for the preparation of other chemical compounds. Its reactivity and structural features make it a useful component in the creation of a range of organic molecules, contributing to the broader field of chemical research and development.
Safety Considerations:
It is crucial to handle 5-fluoro-2-nitropyridin-3-ol with care due to its classification as a hazardous chemical. Adherence to standard safety procedures during its handling and storage is essential to ensure the safety of individuals and the environment.

Upstream product

• 209328-55-2 3-fluoro-5-hydroxypyridine 

Downstream Products

• 1003711-04-3 2-amino-3-hydroxy-5-fluoropyridine 
• 1609165-58-3 8-[(2,6-difluorobenzyl)oxy]-6-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid 
• 1609341-55-0 N-(2-amino-2-methylpropyl)-8-[(2,6-difluorobenzyl)oxy]-6-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxamide 

Relevant articles and documents

ARYL- AND HETARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDES AND USE THEREOF

The present application relates to novel aryl- and hetaryl-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.

Hydroxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

BIPYRIDYL AMINES AND ETHERS AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5

The present invention is directed to novel bipyridyl amine and ether compounds such as those of Formula (I): (I) (where R?1#191, R?2#191, R?3#191, X and Y are as defined herein) which are mGluR5 modulators useful in the treatment or prevention of diseases and conditions in which mGluR5 is involved, including but not limited to psychiatric and mood disorders such as schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson’s disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders, such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal, obesity and other diseases. The invention is also directed to pharmaceutical compositions comprising these compounds. This invention further provides a method of treatment of these disorders and conditions by the administration of an effective amount of these novel bipyridyl amine and/or ether compounds and/or compositions containing these compounds.